COBINMA
Deseño, síntese e avaliación médica de compostos bioactivos e novos mateiriais
Publicacións (114) Publicacións nas que participase algún/ha investigador/a
2025
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Hypoxia Compromises the Differentiation of Human Osteosarcoma Cells to CAR-R, a Hydroxylated Derivative of Lithocholic Acid and Potent Agonist of the Vitamin D Receptor
International Journal of Molecular Sciences, Vol. 26, Núm. 1
2024
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A vitamin D-based strategy overcomes chemoresistance in prostate cancer
British Journal of Pharmacology, Vol. 181, Núm. 21, pp. 4279-4293
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First Sila-Vitamin D Analogues: Design, Synthesis, Structural Analysis and Biological Activity
Journal of Medicinal Chemistry, Vol. 67, Núm. 23, pp. 21505-21519
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Pd(0)-Catalyzed-Mediated Synthesis of Vitamin D Compounds
Advanced Synthesis and Catalysis, Vol. 366, Núm. 4, pp. 603-616
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p63 controls metabolic activation of hepatic stellate cells and fibrosis via an HER2-ACC1 pathway
Cell Reports Medicine, Vol. 5, Núm. 2
2023
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Corrigendum to “Lithocholic acid-based design of noncalcemic vitamin D receptor agonists” [Bioorg. Chem. 111 (2021) 104878] (Bioorganic Chemistry (2021) 111, (S0045206821002558), (10.1016/j.bioorg.2021.104878))
Bioorganic Chemistry
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Facile generation of surface diversity in gold nanoparticles
Journal of Colloid and Interface Science, Vol. 641, pp. 719-728
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Further Studies on the Highly Active Des-C-Ring and Aromatic-D-Ring Analogues of 1α,25-Dihydroxyvitamin D3 (Calcitriol): Refinement of the Side Chain
Journal of Medicinal Chemistry, Vol. 66, Núm. 22, pp. 15326-15339
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Hepatic p63 regulates glucose metabolism by repressing SIRT1
Gut, Vol. 72, Núm. 3, pp. 472-483
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Insight Into Factors Governing Formation, Synthesis and Stereochemical Configuration of DNA Adducts Formed by Mitomycins
Chemical Record, Vol. 23, Núm. 1
2022
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Conditioned Medium from Human Uterine Cervical Stem Cells Regulates Oxidative Stress and Angiogenesis of Retinal Pigment Epithelial Cells
Ophthalmic research, Vol. 65, Núm. 5, pp. 556-565
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Design, Synthesis, Biological Activity, and Structural Analysis of Novel Des-C-Ring and Aromatic-D-Ring Analogues of 1α,25-Dihydroxyvitamin D3
Journal of Medicinal Chemistry, Vol. 65, Núm. 19, pp. 13112-13124
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Efficient Asymmetric Synthesis of an A-Ring Synthon for Pd-Catalyzed Preparation of 1α-Hydroxyvitamin D Metabolites and Analogs
European Journal of Organic Chemistry, Vol. 2022, Núm. 33
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GCKIII (Germinal Center Kinase III) Kinases STK24 and STK25 (Serine/Threonine Kinase 24 and 25) Inhibit Cavernoma Development
Stroke, Vol. 53, Núm. 3, pp. 976-986
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In Vivo Effects of Conditioned Medium from Human Uterine Cervical Stem Cells in an Ovarian Cancer Xenograft Mouse Model
Cancer genomics & proteomics, Vol. 19, Núm. 5, pp. 570-575
2021
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Anti-inflammatory effect of tacrolimus/hydroxypropyl-β-cyclodextrin eye drops in an endotoxin-induced uveitis model
Pharmaceutics, Vol. 13, Núm. 10
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Assessment of biological matrices for the detection of in utero cannabis exposure
Drug Testing and Analysis, Vol. 13, Núm. 7, pp. 1371-1382
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Design, Synthesis, Evaluation and Structure of Allenic 1α,25-Dihydroxyvitamin D3 Analogs with Locked Mobility at C-17
Chemistry - A European Journal, Vol. 27, Núm. 53, pp. 13384-13389
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Design, synthesis and evaluation of side-chain hydroxylated derivatives of lithocholic acid as potent agonists of the vitamin D receptor (VDR)
Bioorganic Chemistry, Vol. 115
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LIPG endothelial lipase and breast cancer risk by subtypes
Scientific Reports, Vol. 11, Núm. 1