Toxinas mariñas: mecanismos de transducción, usos terapéuticos e métodos de detección
FARMATOX
Scripps Research Institute
San Diego, Estados UnidosPublicacións en colaboración con investigadores/as de Scripps Research Institute (14)
2021
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Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1
Autophagy, Vol. 17, Núm. 1, pp. 1-382
2016
2014
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In vitro chronic effects on hERG channel caused by the marine biotoxin azaspiracid-2
Toxicon, Vol. 91, pp. 69-75
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In vivo arrhythmogenicity of the marine biotoxin azaspiracid-2 in rats
Archives of Toxicology, Vol. 88, Núm. 2, pp. 425-434
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Microsphere-based immunoassay for the detection of azaspiracids
Analytical Biochemistry, Vol. 447, Núm. 1, pp. 58-63
2010
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Cell volume decrease as a link between azaspiracid-induced cytotoxicity and c-Jun-N-terminal kinase activation in cultured neurons
Toxicological Sciences, Vol. 113, Núm. 1, pp. 158-168
2008
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Azaspiracid substituent at C1 is relevant to in vitro toxicity
Chemical Research in Toxicology, Vol. 21, Núm. 9, pp. 1823-1831
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Cytotoxic effect of azaspiracid-2 and azaspiracid-2-methyl ester in cultured neurons: Involvement of the c-Jun N-terminal kinase
Journal of Neuroscience Research, Vol. 86, Núm. 13, pp. 2952-2962
2007
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Effects of azaspiracid-1, a potent cytotoxic agent, on primary neuronal cultures. A structure-activity relationship study
Journal of Medicinal Chemistry, Vol. 50, Núm. 2, pp. 356-363
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Irreversible cytoskeletal disarrangement is independent of caspase activation during in vitro azaspiracid toxicity in human neuroblastoma cells
Biochemical Pharmacology, Vol. 74, Núm. 2, pp. 327-335
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The c-Jun-N-terminal kinase is involved in the neurotoxic effect of azaspiracid-1
Cellular Physiology and Biochemistry, Vol. 20, Núm. 6, pp. 957-966
2006
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Azaspiracids modulate intracellular pH levels in human lymphocytes
Biochemical and Biophysical Research Communications, Vol. 346, Núm. 3, pp. 1091-1099
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Cell growth inhibition and actin cytoskeleton disorganization induced by azaspiracid-1 structure-activity studies
Chemical Research in Toxicology, Vol. 19, Núm. 11, pp. 1459-1466