Toxinas mariñas: mecanismos de transducción, usos terapéuticos e métodos de detección
FARMATOX
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Japan Food Research Laboratories
Tokio, JapónPublicacións en colaboración con investigadores/as de Japan Food Research Laboratories (18)
2010
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Impact of the pectenotoxin C-43 oxidation degree on its cytotoxic effect on rat hepatocytes
Chemical Research in Toxicology, Vol. 23, Núm. 3, pp. 504-515
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The methyl ester of okadaic acid is more potent than okadaic acid in disrupting the actin cytoskeleton and metabolism of primary cultured hepatocytes
British Journal of Pharmacology, Vol. 159, Núm. 2, pp. 337-344
2008
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Assessment of the hydrolysis process for the determination of okadaic acid-group toxin ester: Presence of okadaic acid 7-O-acyl-ester derivates in Spanish shellfish
Toxicon, Vol. 51, Núm. 5, pp. 765-773
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Cytoskeletal toxicity of pectenotoxins in hepatic cells
British Journal of Pharmacology, Vol. 155, Núm. 6, pp. 934-944
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Feasibility of using a surface plasmon resonance-based biosensor to detect and quantify yessotoxin
Analytica Chimica Acta, Vol. 617, Núm. 1-2, pp. 167-170
2007
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Extraction and cleaning methods to detect yessotoxins in contaminated mussels
Analytical Biochemistry, Vol. 363, Núm. 2, pp. 228-238
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Lactone ring of pectenotoxins: A key factor for their activity on cytoskeletal dynamics
Cellular Physiology and Biochemistry, Vol. 19, Núm. 5-6, pp. 283-292
2006
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Study of the interaction between different phosphodiesterases and yessotoxin using a resonant mirror biosensor
Chemical Research in Toxicology, Vol. 19, Núm. 6, pp. 794-800
2005
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Actin cytoskeleton of rabbit intestinal cells is a target for potent marine phycotoxins
Journal of Experimental Biology, Vol. 208, Núm. 22, pp. 4345-4354
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Azaspiracid-4 inhibits Ca2+ entry by stored operated channels in human T lymphocytes
Biochemical Pharmacology, Vol. 69, Núm. 11, pp. 1627-1636
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Kinetic analysis of the interaction between yessotoxin and analogues and immobilized phosphodiesterases using a resonant mirror optical biosensor
Chemical Research in Toxicology, Vol. 18, Núm. 7, pp. 1155-1160
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Quantification of yessotoxin using the fluorescence polarization technique and study of the adequate extraction procedure
Analytical Biochemistry, Vol. 344, Núm. 2, pp. 266-274
2004
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A rapid microplate fluorescence method to detect yessotoxins based on their capacity to activate phosphodiesterases
Analytical Biochemistry, Vol. 326, Núm. 1, pp. 93-99
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Detection of Sodium Channel Activators by a Rapid Fluorimetric Microplate Assay
Chemical Research in Toxicology, Vol. 17, Núm. 4, pp. 572-578
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Effects of azaspiracids 2 and 3 on intracellular cAMP, [Ca2+], and pH
Chemical Research in Toxicology, Vol. 17, Núm. 10, pp. 1338-1349
2003
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Yessotoxin, a novel phycotoxin, activates phosphodiesterase activity: Effect of yessotoxin on cAMP levels in human lymphocytes
Biochemical Pharmacology, Vol. 65, Núm. 2, pp. 193-208
2002
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Azaspiracid-1, a potent, nonapoptotic new phycotoxin with several cell targets
Cellular Signalling, Vol. 14, Núm. 8, pp. 703-716
2001
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Maitotoxin-induced calcium entry in human lymphocytes - Modulation by yessotoxin, Ca2+ channel blockers and kinases
Cellular Signalling, Vol. 13, Núm. 10, pp. 711-716