I+D de fármacos
GI-1606
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Instituto Politécnico do Porto
Oporto, PortugalPublicacións en colaboración con investigadores/as de Instituto Politécnico do Porto (8)
2019
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Benzoic acid-derived nitrones: A new class of potential acetylcholinesterase inhibitors and neuroprotective agents
European Journal of Medicinal Chemistry, Vol. 174, pp. 116-129
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Fine-tuning the neuroprotective and blood-brain barrier permeability profile of multi-target agents designed to prevent progressive mitochondrial dysfunction
European Journal of Medicinal Chemistry, Vol. 167, pp. 525-545
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Insights into the discovery of novel neuroprotective agents: A comparative study between sulfanylcinnamic acid derivatives and related phenolic analogues
Molecules, Vol. 24, Núm. 23
2018
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Hydroxybenzoic acid derivatives as dual-target ligands: Mitochondriotropic antioxidants and cholinesterase inhibitors
Frontiers in Chemistry, Vol. 6, Núm. APR
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PEGylated PLGA Nanoparticles As a Smart Carrier to Increase the Cellular Uptake of a Coumarin-Based Monoamine Oxidase B Inhibitor
ACS Applied Materials and Interfaces, Vol. 10, Núm. 46, pp. 39557-39569
2016
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Development of blood-brain barrier permeable nitrocatechol-based catechol O-methyltransferase inhibitors with reduced potential for hepatotoxicity
Journal of Medicinal Chemistry, Vol. 59, Núm. 16, pp. 7584-7597
2014
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Chromone: A valid scaffold in medicinal chemistry
Chemical Reviews, Vol. 114, Núm. 9, pp. 4960-4992
2007
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Electrochemical and spectroscopic characterisation of amphetamine-like drugs: Application to the screening of 3,4-methylenedioxymethamphetamine (MDMA) and its synthetic precursors
Analytica Chimica Acta, Vol. 596, Núm. 2, pp. 231-241