I+D de fármacos
GI-1606
![Foto de María Fernanda](/img/nophoto.png)
María Fernanda
Borges
Publicacións nas que colabora con María Fernanda Borges (79)
2023
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2H-chromene and 7H-furo-chromene derivatives selectively inhibit tumour associated human carbonic anhydrase IX and XII isoforms
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol. 38, Núm. 1
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8-Amide and 8-carbamate substitution patterns as modulators of 7-hydroxy-4-methylcoumarin's antidepressant profile: Synthesis, biological evaluation and docking studies
European Journal of Medicinal Chemistry, Vol. 248
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Modulating Cytotoxicity with Lego-like Chemistry: Upgrading Mitochondriotropic Antioxidants with Prototypical Cationic Carrier Bricks
Journal of Medicinal Chemistry, Vol. 66, Núm. 3, pp. 1835-1851
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Propargylamine: an important moiety in drug discovery
Future Medicinal Chemistry, Vol. 15, Núm. 1, pp. 211-224
2022
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Coumarin-Resveratrol-Inspired Hybrids as Monoamine Oxidase B Inhibitors: 3-Phenylcoumarin versus trans-6-Styrylcoumarin
Molecules, Vol. 27, Núm. 3
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Design and synthesis of chromone-based monoamine oxidase B inhibitors with improved drug-like properties
European Journal of Medicinal Chemistry, Vol. 239
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Thiocoumarins: From the Synthesis to the Biological Applications
Molecules, Vol. 27, Núm. 15
2021
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4-Oxoquinolines and monoamine oxidase: When tautomerism matters
European Journal of Medicinal Chemistry, Vol. 213
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Chemical and biological analysis of 4-acyloxy-3-nitrocoumarins as trypanocidal agents
Arabian Journal of Chemistry, Vol. 14, Núm. 3
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Computer-aided Design of Coumarins for Neurodegenerative Diseases: Trends of the Last Decade
Current topics in medicinal chemistry, Vol. 21, Núm. 25, pp. 2245-2257
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Study of a Selected Series of 3- and 4-Arylcoumarins as Antifungal Agents against Dermatophytic Fungi: T. rubrum and T. mentagrophytes
ChemistrySelect, Vol. 6, Núm. 37, pp. 9981-9989
2020
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Adenosine receptor ligands: Coumarin–Chalcone hybrids as modulating agents on the activity of hARs
Molecules, Vol. 25, Núm. 18
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Exploring the multi-target performance of mitochondriotropic antioxidants against the pivotal Alzheimer’s disease pathophysiological hallmarks
Molecules, Vol. 25, Núm. 2
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Looking for new xanthine oxidase inhibitors: 3-Phenylcoumarins versus 2-phenylbenzofurans
International Journal of Biological Macromolecules, Vol. 162, pp. 774-780
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Structure-Based Optimization of Coumarin hA3 Adenosine Receptor Antagonists
Journal of Medicinal Chemistry, Vol. 63, Núm. 5, pp. 2577-2587
2019
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Benzoic acid-derived nitrones: A new class of potential acetylcholinesterase inhibitors and neuroprotective agents
European Journal of Medicinal Chemistry, Vol. 174, pp. 116-129
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Fine-tuning the neuroprotective and blood-brain barrier permeability profile of multi-target agents designed to prevent progressive mitochondrial dysfunction
European Journal of Medicinal Chemistry, Vol. 167, pp. 525-545
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Insights into the discovery of novel neuroprotective agents: A comparative study between sulfanylcinnamic acid derivatives and related phenolic analogues
Molecules, Vol. 24, Núm. 23
2018
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Correction to: Discovery of New Chemical Entities for Old Targets: Insights on the Lead Optimization of Chromone-Based Monoamine Oxidase B (MAO-B) Inhibitors (Journal of Medicinal Chemistry (2016) 59 (5879-5893) DOI: 10.1021/acs.jmedchem.6b00527)
Journal of Medicinal Chemistry
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Coumarins and adenosine receptors: New perceptions in structure–affinity relationships
Chemical Biology and Drug Design, Vol. 91, Núm. 1, pp. 245-256