I+D de fármacos
GI-1606
![Foto de Enrique](/img/nophoto.png)
Enrique
Raviña Rubira
Publicacións nas que colabora con Enrique Raviña Rubira (60)
2017
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3-Oxopyridazin-5-yl-Chalcone Hybrids: Potent Antiplatelet Agents That Prevent Glycoprotein IIb/IIIa Activation
ChemistrySelect, Vol. 2, Núm. 17, pp. 4920-4933
2014
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Synthesis and biological evaluation of a series of aminoalkyl-tetralones and tetralols as dual dopamine/serotonin ligands
European Journal of Medicinal Chemistry, Vol. 71, pp. 237-249
2011
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Potential atypical antipsychotics: Synthesis, binding affinity and SAR of new heterocyclic bioisosteric butyrophenone analogues as multitarget ligands
MedChemComm, Vol. 2, Núm. 12, pp. 1194-1200
2009
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Synthesis and binding affinity of potential atypical antipsychotics with the tetrahydroquinazolinone motif
Bioorganic and Medicinal Chemistry Letters, Vol. 19, Núm. 21, pp. 6059-6062
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Synthesis, binding affinity and SAR of new benzolactam derivatives as dopamine D3 receptor ligands
Bioorganic and Medicinal Chemistry Letters, Vol. 19, Núm. 6, pp. 1773-1778
2008
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Synthesis, binding affinity, and molecular docking analysis of new benzofuranone derivatives as potential antipsychotics
Journal of Medicinal Chemistry, Vol. 51, Núm. 19, pp. 6085-6094
2007
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Design, synthesis, and structure-activity relationships of a novel series of 5-alkylidenepyridazin-3(2H)-ones with a non-cAMP-based antiplatelet activity
Journal of Medicinal Chemistry, Vol. 50, Núm. 26, pp. 6476-6484
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Multistructure 3D-QSAR studies on a series of conformationally constrained butyrophenones docked into a new homology model of the 5-HT2A receptor
Journal of Medicinal Chemistry, Vol. 50, Núm. 14, pp. 3242-3255
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Synthesis and binding affinity of new pyrazole and isoxazole derivatives as potential atypical antipsychotics
Bioorganic and Medicinal Chemistry Letters, Vol. 17, Núm. 17, pp. 4873-4877
2006
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Efficient consecutive alkylation-Knoevenagel functionalisations in formyl aza-heterocycles using supported organic bases
Synlett, pp. 3324-3328
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Pyridazines part 41: Synthesis, antiplatelet activity and SAR of 2,4,6-substituted 5-(3-oxo-3-phenylprop-1-en-1-yl)- or 5-(3-phenylprop-2-enoyl) pyridazin-3(2H)-ones
Bioorganic and Medicinal Chemistry Letters, Vol. 16, Núm. 4, pp. 1080-1083
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QF2004B, a potential antipsychotic butyrophenone derivative with similar pharmacological properties to clozapine
Neuropharmacology, Vol. 51, Núm. 2, pp. 251-262
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Synthesis and biological evaluation of new quinazoline and cinnoline derivatives as potential atypical antipsychotics
Chemistry and Biodiversity, Vol. 3, Núm. 1, pp. 106-117
2005
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Synthesis and binding affinity of novel 3-aminoethyl-1-tetralones, potential atypical antipsychotics
Bioorganic and Medicinal Chemistry Letters, Vol. 15, Núm. 12, pp. 3063-3066
2004
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Chemoenzymatic synthesis and binding affinity of novel (R)- and (S)-3-aminomethyl-1-tetralones, potential atypical antipsychotics
Bioorganic and Medicinal Chemistry Letters, Vol. 14, Núm. 3, pp. 585-589
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Pyridazine derivatives. Part 38: Efficient Heck alkenylation at position 5 of the 6-phenyl-3(2H)-pyridazinone system
Tetrahedron Letters, Vol. 45, Núm. 17, pp. 3459-3463
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Pyridazine derivatives. Part 39: Reactivity of 5-iodopyridazin-3(2H)-ones in palladium-catalysed reactions
Tetrahedron, Vol. 60, Núm. 52, pp. 12177-12189
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Pyridazines. Part 36: Synthesis and antiplatelet activity of 5-substituted-6-phenyl-3(2H)-pyridazinones
Bioorganic and Medicinal Chemistry Letters, Vol. 14, Núm. 2, pp. 321-324
2003
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Conformationally constrained butyrophenones as new pharmacological tools to study 5-HT2A and 5-HT2C receptor behaviours
European Journal of Medicinal Chemistry
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In vivo and in vitro pharmacological studies of a new hypotensive compound (QF0301B) in rat: Comparison with prazosin, a known α1- adrenoceptor antagonist
Vascular Pharmacology, Vol. 40, Núm. 2, pp. 97-108