Asymmetric drug synthesis and enantiospecific modulation of biological targets: applications in the treatment of neurodegenerative pathologies.
Asymmetric induction in aza-Diels-Alder reactions with azadienophiles
Control of selectivity in C-C bond formation reactions and study of the structure, stability and reactivity of polyfunctionalized organolithium compounds.
Design and synthesis of novel farmacological tools for the study of complex targets: Fluorescent Ligands, Homo- and Heterobivalent Ligands
Design, synthesis and evaluation of novel rasagiline related neuroprotective agents
Design, Synthesis and Structure-Activity Relationship of heterocyclic compounds libraries with diverse farmacological activities
Development and exploitation of new synthetic methodologies in Combinatorial Chemistry. Multicomponent Reactions
Synthesis of novel proline related peptidomimetics with neuroprotective activity