Descubrimento e síntese de fármacos
Desinfarma
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Aarhus University
Århus, DinamarcaPublicacións en colaboración con investigadores/as de Aarhus University (5)
2022
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Synthesis of hybrid phosphorated indenoquinolines and biological evaluation as topoisomerase I inhibitors and antiproliferative agents
Bioorganic and Medicinal Chemistry Letters, Vol. 57
2021
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Hybrid quinolinyl phosphonates as heterocyclic carboxylate isosteres: Synthesis and biological evaluation against topoisomerase 1b (top1b)
Pharmaceuticals, Vol. 14, Núm. 8
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Simple and fast dna based sensor system for screening of small-molecule compounds targeting eukaryotic topoisomerase 1
Pharmaceutics, Vol. 13, Núm. 8
2020
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Synthesis of novel hybrid quinolino[4,3-b][1,5]naphthyridines and quinolino[4,3-b][1,5]naphthyridin-6(5H)-one derivatives and biological evaluation as topoisomerase I inhibitors and antiproliferatives
European Journal of Medicinal Chemistry, Vol. 195
2018
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Novel topoisomerase I inhibitors. Syntheses and biological evaluation of phosphorus substituted quinoline derivates with antiproliferative activity
European Journal of Medicinal Chemistry, Vol. 149, pp. 225-237