Descubrimento e síntese de fármacos
Desinfarma
KU Leuven
Lovaina, BélgicaPublicacións en colaboración con investigadores/as de KU Leuven (25)
2010
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A 'click chemistry' approach to the straightforward synthesis of new 4-aryl-1,2,3-triazolocarbanucleosides
Arkivoc, Vol. 2010, Núm. 3, pp. 152-168
2009
2008
2007
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Synthesis of 4-substituted-1,2,3-triazole carbanucleoside analogues of ribavirin via click chemistry
Organic and Biomolecular Chemistry, Vol. 5, Núm. 23, pp. 3805-3813
2005
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Pyridazine derivatives. Part 40: Reactivity of 5-alkynylpyridazin-3(2H)- ones toward hydrochloric acid
Tetrahedron, Vol. 61, Núm. 20, pp. 4785-4791
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Synthesis of purinyl homo-carbonucleoside derivatives of 2-benzylcyclopenta[c]pyrazol
Synthesis, pp. 925-932
2004
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A convenient synthesis of new purinyl-homo-carbonucleosides on a cyclopentane ring fused with pyridazine
Synthesis, pp. 2855-2862
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Pyridazine derivatives. Part 38: Efficient Heck alkenylation at position 5 of the 6-phenyl-3(2H)-pyridazinone system
Tetrahedron Letters, Vol. 45, Núm. 17, pp. 3459-3463
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Pyridazine derivatives. Part 39: Reactivity of 5-iodopyridazin-3(2H)-ones in palladium-catalysed reactions
Tetrahedron, Vol. 60, Núm. 52, pp. 12177-12189
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Synthesis and biological evaluation of carbocyclic nucleosides with 2′,3′-dihomo-xylo-carbocyclic or carbocyclic fused to a tetrahydrofuran ring
Synthesis, pp. 1991-1995
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Synthesis of new 6-substituted purinyl-5′-nor-1′- homocarbanucleosides based on indanol
Tetrahedron, Vol. 60, Núm. 41, pp. 9245-9253
2003
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Carbocyclic analogues of nucleosides from bis-(hydroxymethyl)-cyclopentane: Synthesis, antiviral and cytostatic activities of adenosine, inosine and uridine analogues
Chemical and Pharmaceutical Bulletin, Vol. 51, Núm. 9, pp. 1060-1063
2002
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Synthesis and cytostatic activities of new 6-substituted purinylcarbonucleosides derived from indan
Synthesis, pp. 1084-1090
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Synthesis, antiviral and cytostatic activities, of carbocyclic nucleosides incorporating a modified cyclopentane ring. IV. Adenosine and uridine analogues
Nucleosides, Nucleotides and Nucleic Acids, Vol. 21, Núm. 3, pp. 243-255
2000
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5-Amino-6-phenyl-1,6-dihydropyridazin-3(2H)-one
Acta Crystallographica Section C: Crystal Structure Communications, Vol. 56, Núm. 3, pp. 345-346
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Pyridazine derivatives. Part 21: Synthesis and structural study of novel 4-aryl-2,5-dioxo-8-phenylpyrido[2,3-d]pyridazines
Tetrahedron, Vol. 56, Núm. 16, pp. 2473-2479
1999
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Synthesis and antiviral activity of carbocyclic nucleosides incorporating a modified cyclopentane ring. Part 3: Adenosine and uridine analogues
Nucleosides and Nucleotides, Vol. 18, Núm. 10, pp. 2253-2263
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Synthesis and antiviral and antineoplastic activities of some novel carbocyclic guanosine analogues with a cyclobutane ring
Chemical and Pharmaceutical Bulletin, Vol. 47, Núm. 9, pp. 1314-1317
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Synthesis and antiviral and cytostatic activities of carbocyclic nucleosides incorporating a modified cyclobutane ring. Part 1: Guanosine analogues
Archiv der Pharmazie, Vol. 332, Núm. 10, pp. 348-352
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Synthesis of novel carbocyclic nucleosides with a modified cyclopentane ring and evaluation of their antiviral activity
Nucleosides and Nucleotides