Descubrimento e síntese de fármacos
Desinfarma
University of Antwerp
Amberes, BélgicaPublikationen in Zusammenarbeit mit Forschern von University of Antwerp (3)
2008
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2-Substituted 4-, 5-, and 6-[(1E)-3-oxo-3-phenylprop-1-en-1-yl]pyridazin-3(2H)-ones and 2-substituted 4,5-bis[(1E)-3-oxo-3-phenylprop-1-en-1-yl]pyridazin-3(2H)-ones as potent platelet aggregation inhibitors: Design, synthesis, and SAR studies
Bioorganic and Medicinal Chemistry Letters, Vol. 18, Núm. 2, pp. 793-797
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Auto-tandem catalysis: Synthesis of substituted 11H-indolo [3,2-c]quinolines via palladium-catalyzed intermolecular C-N and intramolecular C-C bond formation
Advanced Synthesis and Catalysis, Vol. 350, Núm. 3, pp. 465-470
2006
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Pyridazines part 41: Synthesis, antiplatelet activity and SAR of 2,4,6-substituted 5-(3-oxo-3-phenylprop-1-en-1-yl)- or 5-(3-phenylprop-2-enoyl) pyridazin-3(2H)-ones
Bioorganic and Medicinal Chemistry Letters, Vol. 16, Núm. 4, pp. 1080-1083