Publicacións en colaboración con investigadores/as de Universidad del País Vasco/Euskal Herriko Unibertsitatea (24)

2022

  1. Synthesis of hybrid phosphorated indenoquinolines and biological evaluation as topoisomerase I inhibitors and antiproliferative agents

    Bioorganic and Medicinal Chemistry Letters, Vol. 57

  2. The design and discovery of topoisomerase I inhibitors as anticancer therapies

    Expert Opinion on Drug Discovery, Vol. 17, Núm. 6, pp. 581-601

2021

  1. A patent review of topoisomerase I inhibitors (2016–present)

    Expert Opinion on Therapeutic Patents, Vol. 31, Núm. 6, pp. 473-508

  2. Design, synthesis and cytotoxic evaluation of diphenyl(quinolin-8-yl)phosphine oxides

    Tetrahedron Letters, Vol. 70

  3. Hybrid quinolinyl phosphonates as heterocyclic carboxylate isosteres: Synthesis and biological evaluation against topoisomerase 1b (top1b)

    Pharmaceuticals, Vol. 14, Núm. 8

  4. Simple and fast dna based sensor system for screening of small-molecule compounds targeting eukaryotic topoisomerase 1

    Pharmaceutics, Vol. 13, Núm. 8

  5. Synthesis, Pharmacological, and Biological Evaluation of 2-Furoyl-Based MIF-1 Peptidomimetics and the Development of a General-Purpose Model for Allosteric Modulators (ALLOPTML)

    ACS Chemical Neuroscience, Vol. 12, Núm. 1, pp. 203-215

2020

  1. Fused 1,5-Naphthyridines: Synthetic Tools and Applications

    Molecules (Basel, Switzerland), Vol. 25, Núm. 15

  2. Synthesis of novel hybrid quinolino[4,3-b][1,5]naphthyridines and quinolino[4,3-b][1,5]naphthyridin-6(5H)-one derivatives and biological evaluation as topoisomerase I inhibitors and antiproliferatives

    European Journal of Medicinal Chemistry, Vol. 195

  3. Synthetic strategies, reactivity and applications of 1,5-naphthyridines

    Molecules, Vol. 25, Núm. 14

2019

  1. Antileishmanial activity of new hybrid tetrahydroquinoline and quinoline derivatives with phosphorus substituents

    European Journal of Medicinal Chemistry, Vol. 162, pp. 18-31

  2. Multicatalysis Combining 3D-Printed Devices and Magnetic Nanoparticles in One-Pot Reactions: Steps Forward in Compartmentation and Recyclability of Catalysts

    ACS Applied Materials and Interfaces, Vol. 11, Núm. 28, pp. 25283-25294

  3. Perturbation Theory Machine Learning Modeling of Immunotoxicity for Drugs Targeting Inflammatory Cytokines and Study of the Antimicrobial G1 Using Cytometric Bead Arrays

    Chemical Research in Toxicology, Vol. 32, Núm. 9, pp. 1811-1823

2018

  1. Novel topoisomerase I inhibitors. Syntheses and biological evaluation of phosphorus substituted quinoline derivates with antiproliferative activity

    European Journal of Medicinal Chemistry, Vol. 149, pp. 225-237

  2. Perturbation Theory/Machine Learning Model of ChEMBL Data for Dopamine Targets: Docking, Synthesis, and Assay of New l -Prolyl- l -leucyl-glycinamide Peptidomimetics

    ACS Chemical Neuroscience, Vol. 9, Núm. 11, pp. 2572-2587

  3. Three-Dimensional Printing in Catalysis: Combining 3D Heterogeneous Copper and Palladium Catalysts for Multicatalytic Multicomponent Reactions

    ACS Catalysis, Vol. 8, Núm. 1, pp. 392-404

2017

  1. Multi-target mining of alzheimer disease proteome with Hansch’s QSBR-perturbation theory and experimental-theoretic study of new thiophene isosters of rasagiline

    Current Drug Targets, Vol. 18, Núm. 5, pp. 511-521

2016

  1. Brain-inspired cheminformatics of drug-target brain interactome, synthesis, and assay of TVP1022 derivatives

    Neuropharmacology, Vol. 103, pp. 270-278

  2. Experimental-theoretic approach to drug-lymphocyte interactome networks with flow cytometry and spectral moments perturbation theory

    Current Pharmaceutical Design, Vol. 22, Núm. 33, pp. 5114-5119

2014

  1. Model for high-throughput screening of drug immunotoxicity - Study of the anti-microbial G1 over peritoneal macrophages using flow cytometry

    European Journal of Medicinal Chemistry, Vol. 72, pp. 206-220