Descubrimento e síntese de fármacos
Desinfarma
Joana Raquel
Ferreira da Costa
Publicacións nas que colabora con Joana Raquel Ferreira da Costa (5)
2018
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Perturbation Theory/Machine Learning Model of ChEMBL Data for Dopamine Targets: Docking, Synthesis, and Assay of New l -Prolyl- l -leucyl-glycinamide Peptidomimetics
ACS Chemical Neuroscience, Vol. 9, Núm. 11, pp. 2572-2587
2016
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Novel l-prolyl-l-leucylglycinamide (PLG) tripeptidomimetics based on a 2-azanorbornane scaffold as positive allosteric modulators of the D2R
Organic and Biomolecular Chemistry, Vol. 14, Núm. 47, pp. 11065-11069
2015
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Synthesis by microwave-assisted 1,3-dipolar cycloaddition of 1,2,3-triazole 1'-homo-3'-isoazanucleosides and evaluation of their anticancer activity
European Journal of Medicinal Chemistry, Vol. 98, pp. 212-220
2013
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Synthesis and allosteric modulation of the dopamine receptor by peptide analogs of l-prolyl-l-leucyl-glycinamide (PLG) modified in the l-proline or l-proline and l-leucine scaffolds
European Journal of Medicinal Chemistry, Vol. 69, pp. 146-158
2010
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Synthesis of methyl (±)-3,5-bis(substitutedmethyl)pyrrolidine-2- carboxylates: A convenient approach to proline-mimetics
Tetrahedron, Vol. 66, Núm. 34, pp. 6797-6805