Publications by the researcher in collaboration with MARIA REYES LAGUNA FRANCIA (9)

2017

  1. 3-Oxopyridazin-5-yl-Chalcone Hybrids: Potent Antiplatelet Agents That Prevent Glycoprotein IIb/IIIa Activation

    ChemistrySelect, Vol. 2, Núm. 17, pp. 4920-4933

2008

  1. 2-Substituted 4-, 5-, and 6-[(1E)-3-oxo-3-phenylprop-1-en-1-yl]pyridazin-3(2H)-ones and 2-substituted 4,5-bis[(1E)-3-oxo-3-phenylprop-1-en-1-yl]pyridazin-3(2H)-ones as potent platelet aggregation inhibitors: Design, synthesis, and SAR studies

    Bioorganic and Medicinal Chemistry Letters, Vol. 18, Núm. 2, pp. 793-797

2007

  1. Design, synthesis, and structure-activity relationships of a novel series of 5-alkylidenepyridazin-3(2H)-ones with a non-cAMP-based antiplatelet activity

    Journal of Medicinal Chemistry, Vol. 50, Núm. 26, pp. 6476-6484

2006

  1. Pyridazines part 41: Synthesis, antiplatelet activity and SAR of 2,4,6-substituted 5-(3-oxo-3-phenylprop-1-en-1-yl)- or 5-(3-phenylprop-2-enoyl) pyridazin-3(2H)-ones

    Bioorganic and Medicinal Chemistry Letters, Vol. 16, Núm. 4, pp. 1080-1083

2004

  1. Pyridazines. Part 36: Synthesis and antiplatelet activity of 5-substituted-6-phenyl-3(2H)-pyridazinones

    Bioorganic and Medicinal Chemistry Letters, Vol. 14, Núm. 2, pp. 321-324

2002

  1. Pyridazines. Part 28: 5-Alkylidene-6-phenyl-3(2H)-pyridazinones, a new family of platelet aggregation inhibitors

    Bioorganic and Medicinal Chemistry Letters, Vol. 12, Núm. 12, pp. 1575-1577

  2. Pyridazines. Part 31: Synthesis and antiplatelet activity of 4,5-disubstituted-6-phenyl-3(2H)-pyridazinones

    Chemical and Pharmaceutical Bulletin, Vol. 50, Núm. 12, pp. 1574-1577

  3. Pyridazines. Part XXIX: Synthesis and platelet aggregation inhibition activity of 5-substituted-6-phenyl-3(2H)-pyridazinones. Novel aspects of their biological actions

    Bioorganic and Medicinal Chemistry, Vol. 10, Núm. 9, pp. 2873-2882

1997

  1. Pyridazines. XIII. Synthesis of 6-aryl-5-oxygenated substituted-3(2H)- pyridazinones and evaluation as platelet aggregation inhibitors

    Chemical and Pharmaceutical Bulletin, Vol. 45, Núm. 7, pp. 1151-1155