Control da Regulación Xénica en Enfermidades
Regulación Xénica
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Centro de Investigación Biomédica en Red sobre Enfermedades Hepáticas y Digestivas
Madrid, EspañaPublicacións en colaboración con investigadores/as de Centro de Investigación Biomédica en Red sobre Enfermedades Hepáticas y Digestivas (59)
2024
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Neddylation orchestrates the complex transcriptional and posttranscriptional program that drives Schwann cell myelination
Science Advances, Vol. 10, Núm. 15
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p63 controls metabolic activation of hepatic stellate cells and fibrosis via an HER2-ACC1 pathway
Cell Reports Medicine, Vol. 5, Núm. 2
2023
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Hepatic levels of S-adenosylmethionine regulate the adaptive response to fasting
Cell Metabolism, Vol. 35, Núm. 8, pp. 1373-1389.e8
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Hepatocyte-specific O-GlcNAc transferase downregulation ameliorates nonalcoholic steatohepatitis by improving mitochondrial function
Molecular Metabolism, Vol. 75
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Neddylation of phosphoenolpyruvate carboxykinase 1 controls glucose metabolism
Cell Metabolism, Vol. 35, Núm. 9, pp. 1630-1645.e5
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The outcome of boosting mitochondrial activity in alcohol-associated liver disease is organ-dependent
Hepatology (Baltimore, Md.), Vol. 78, Núm. 3, pp. 878-895
2022
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Evaluation of Blood Soluble CD26 as a Complementary Biomarker for Colorectal Cancer Screening Programs
Cancers, Vol. 14, Núm. 19
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Inhibition of ATG3 ameliorates liver steatosis by increasing mitochondrial function
Journal of Hepatology, Vol. 76, Núm. 1, pp. 11-24
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Inhibition of carnitine palmitoyltransferase 1A in hepatic stellate cells protects against fibrosis
Journal of Hepatology, Vol. 77, Núm. 1, pp. 15-28
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Methionine adenosyltransferase 1a antisense oligonucleotides activate the liver-brown adipose tissue axis preventing obesity and associated hepatosteatosis
Nature Communications, Vol. 13, Núm. 1
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Mitochondrial bioenergetics boost macrophage activation, promoting liver regeneration in metabolically compromised animals
Hepatology, Vol. 75, Núm. 3, pp. 550-566
2021
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Boosting mitochondria activity by silencing MCJ overcomes cholestasis-induced liver injury
JHEP Reports, Vol. 3, Núm. 3
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Magnesium accumulation upon cyclin M4 silencing activates microsomal triglyceride transfer protein improving NASH
Journal of Hepatology, Vol. 75, Núm. 1, pp. 34-45
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O-GlcNAcylated p53 in the liver modulates hepatic glucose production
Nature Communications, Vol. 12, Núm. 1
2020
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HuR/ELAVL1 drives malignant peripheral nerve sheath tumor growth and metastasis
The Journal of clinical investigation, Vol. 130, Núm. 7, pp. 3848-3864
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Silencing hepatic MCJ attenuates non-alcoholic fatty liver disease (NAFLD) by increasing mitochondrial fatty acid oxidation
Nature Communications, Vol. 11, Núm. 1
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Targeting Hepatic Glutaminase 1 Ameliorates Non-alcoholic Steatohepatitis by Restoring Very-Low-Density Lipoprotein Triglyceride Assembly
Cell Metabolism, Vol. 31, Núm. 3, pp. 605-622.e10
2019
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Fine-Tuning of Sirtuin 1 Expression Is Essential to Protect the Liver From Cholestatic Liver Disease
Hepatology, Vol. 69, Núm. 2, pp. 699-716
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SUMOylation regulates LKB1 localization and its oncogenic activity in liver cancer
EBioMedicine, Vol. 40, pp. 406-421
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Ubiquitin-Like Post-Translational Modifications (Ubl-PTMs): Small Peptides with Huge Impact in Liver Fibrosis
Cells, Vol. 8, Núm. 12