Control da Regulación Xénica en Enfermidades
Regulación Xénica
![Foto de Javier](/img/nophoto.png)
Javier
Crespo García
Publicacións nas que colabora con Javier Crespo García (15)
2024
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p63 controls metabolic activation of hepatic stellate cells and fibrosis via an HER2-ACC1 pathway
Cell Reports Medicine, Vol. 5, Núm. 2
2023
2022
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Inhibition of ATG3 ameliorates liver steatosis by increasing mitochondrial function
Journal of Hepatology, Vol. 76, Núm. 1, pp. 11-24
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Inhibition of carnitine palmitoyltransferase 1A in hepatic stellate cells protects against fibrosis
Journal of Hepatology, Vol. 77, Núm. 1, pp. 15-28
2021
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Boosting mitochondria activity by silencing MCJ overcomes cholestasis-induced liver injury
JHEP Reports, Vol. 3, Núm. 3
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E2F1 and E2F2-mediated repression of CPT2 establishes a lipid-rich tumor-promoting environment
Cancer Research, Vol. 81, Núm. 11, pp. 2874-2887
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Magnesium accumulation upon cyclin M4 silencing activates microsomal triglyceride transfer protein improving NASH
Journal of Hepatology, Vol. 75, Núm. 1, pp. 34-45
2020
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Silencing hepatic MCJ attenuates non-alcoholic fatty liver disease (NAFLD) by increasing mitochondrial fatty acid oxidation
Nature Communications, Vol. 11, Núm. 1
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Targeting Hepatic Glutaminase 1 Ameliorates Non-alcoholic Steatohepatitis by Restoring Very-Low-Density Lipoprotein Triglyceride Assembly
Cell Metabolism, Vol. 31, Núm. 3, pp. 605-622.e10
2019
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miR-873-5p targets mitochondrial GNMT-Complex II interface contributing to non-alcoholic fatty liver disease
Molecular Metabolism, Vol. 29, pp. 40-54
2018
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MiR-873-5p acts as an epigenetic regulator in early stages of liver fibrosis and cirrhosis
Cell Death and Disease, Vol. 9, Núm. 10
2017
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A morphological method for ammonia detection in liver
PLoS ONE, Vol. 12, Núm. 3
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Deregulated neddylation in liver fibrosis
Hepatology, Vol. 65, Núm. 2, pp. 694-709
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Metabolomic Identification of Subtypes of Nonalcoholic Steatohepatitis
Gastroenterology, Vol. 152, Núm. 6, pp. 1449-1461.e7
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The mitochondrial negative regulator MCJ is a therapeutic target for acetaminophen-induced liver injury
Nature Communications, Vol. 8, Núm. 1