Correlation between regional brain atrophy, cognitive function, adipose tissue and CSF biomarkers in mild cognitive impairment

  1. Fernández, Miguel Ángel Rivas 1
  2. Lojo‐Seoane, Cristina 1
  3. Galdo‐Álvarez, Santiago 1
  4. Aldrey‐Vázquez, Jose M. 2
  5. Vieites, Ana Nieto 1
  6. Fernández, Alba 1
  7. Pías‐Peleteiro, Juan M. 2
  8. Ferreiro‐Caneiro, Uxia 1
  9. Domínguez‐Vivero, Clara 2
  10. Mallo, Sabela C. 1
  11. Gil, Luis 1
  12. Pereiro, Arturo X. 1
  1. 1 University of Santiago de Compostela Santiago de Compostela Spain
  2. 2 University Hospital of Santiago de Compostela Santiago de Compostela Spain
Journal:
Alzheimer's & Dementia

ISSN: 1552-5260,  1552-5279

Year of publication: 2020

Volume: 16

Issue: S4

Type: Article

DOI: 10.1002/ALZ.042895 GOOGLE SCHOLAR lock_openOpen access editor

More publications in: Alzheimer's & Dementia

Abstract

Characterization of mild cognitive impairment (MCI) for clinical and research purposes involves identification of biological and neuropsychological markers in order to predict possible progression to dementia. The main aim of this work was to analyze the correlation of anthropometric measurements and plasmatic levels of leptin, testosterone and estrogens with cognitive, CSF and MRI regional atrophy markers in a sample of MCI participants