Controlling the ring-chain tautomeric equilibrium of a tetrahydroquinazoline/imine system by steric hindrance
- Sanmartín-Matalobos, Jesús 1
- García-Deibe, Ana 1
- Portela-García, Cristina 1
- Briones-Miguéns, Lucía 1
- Fondo, Matilde 1
- 1 Coordination and Supramolecular Chemistry Group (Suprametal), Institute of Materials (iMATUS), Department of Inorganic Chemistry, Faculty of Chemistry, Universidade de Santiago de Compostela, Avenida das Ciencias s/n, 15782 Santiago de Compostela, Spain
Ano de publicación: 2013
Tipo: Achega congreso
Resumo
We have explored the use of steric hindrance on controlling the ring-chain tautomeric equilibrium of a tetrahydroquinazoline/imine system. Two imines, one of them having a bulky group (E)-N (3-((2-((4-methylphenylsulfonamido)methyl)phenylimino)methyl)pyridin-2-yl)pivalamide (H2L1SB) and the other one without bulky group (E)-N-(2-(2,3-dihydroxybenzylideneamino)-benzyl)-4-methylbenzenesulfonamide (H2L2SB) have been synthetised and spectroscopically studied by 1H NMR. Besides, the formation of the corresponding 1,2,3,4-tetrahydroquinazolines (H2L1TQ and H2L2TQ) was tested.