Development of a simulation platform for the evaluation of PET neuroimaging protocols in epilepsy
- Paredes Pacheco, José
- Pablo Aguiar Fernández Director
- Nuria Roe Vellve Director
Defence university: Universidade de Santiago de Compostela
Fecha de defensa: 16 December 2022
- Xavier Setoain Perego Chair
- Julia Cortés Hernández Secretary
- Alexis Moscoso Rial Committee member
Type: Thesis
Abstract
Monte Carlo simulation of PET studies is a reference tool for the evaluation and standardization of PET protocols. However, current Monte Carlo software codes require a high degree of knowledge in physics, mathematics and programming languages, in addition to a high cost of time and computational resources. These drawbacks make their use difficult for a large part of the scientific community. In order to overcome these limitations, a free and an efficient web-based platform was designed, implemented and validated for the simulation of realistic brain PET studies, and specifically employed for the generation of a wellvalidated large database of brain FDG-PET studies of patients with refractory epilepsy.