Postnatal neurogenesis and molecular characterization of different types of neural progenitor cells in the fish retina

  1. Hernández Núñez, Ismael
Supervised by:
  1. Eva Candal Suárez Director
  2. M. Fátima Adrio Fondevila Director

Defence university: Universidade de Santiago de Compostela

Year of defence: 2022

Committee:
  1. Javier de Francisco Morcillo Chair
  2. Miguel Angel Rodríguez Díaz Secretary
  3. Idoia Quintana Urzainqui Committee member
Department:
  1. Department of Functional Biology

Type: Thesis

Teseo: 710714 DIALNET lock_openMINERVA editor

Abstract

Different regions of the brain in vertebrates appear to have different neurogenic capacity in adults. However, our knowledge of the neurogenic process and the types of neural progenitor cells (NPCs) involved in it comes from a small number of animal models. We expanded the characterization of NPCs to the retina o fishes that, because of its high neurogenic potential at postnatal stages, has resulted advantageous to deepen in the study of postnatal neurogenesis. The main objective of this Thesis is the evaluation of the proliferative potential of the postnatal retina of elasmobranch (catshark) and teleost (zebrafish) fish species, and the identification and molecular characterization of the different types of NPCs of the catshark retina.