Comportamiento a largo plazo de la membrana reabsorbible colágeno-elastina como sustitutivo pericárdico en cirugía coronaria
- Flórez, S.
- Fernández González, Ángel Luis
- Herreros González, Jesús María
- Bustamante, J.
- Ovelar, Y.
- Tamayo, E.
ISSN: 1139-8264
Ano de publicación: 2007
Volume: 10
Número: 1
Páxinas: 11-18
Tipo: Artigo
Outras publicacións en: Revista española de investigaciones quirúrgicas
Resumo
The increase in the amount of reoperations has contributed to highlight the important role of the pericardium in cardiovascular surgery. Once heart disease has been surgically treated, the primary closure of the pericardium prevents the formation of adherences and facilitates a possible re-intervention. Restoring the pericardium continuity is not always possible or advisable due to the fibrotic-adherent reaction, which causes important difficulties and increases morbidity and mortality following reintervention. Many pericardial substitutive materials have been essayed to improve this situation and its consequences, none of them showing satisfactory results. Experimental studies have investigated the effect of a collagen-elastin biodegradable membrane in heart preservation and pericardial regeneration, which seems promising. We present here the short, medium and long term behaviour of this artificial connective tissue matrix in the first clinical trial carried out in patients who have undergone surgical revascularization. Our positive results allow us to guarantee the safety and effectiveness of this pericardial membrane and its ability to reconstitute a new pericardium.