Patología inflamatoria y autoinmune de la vía biliar

  1. Senra, N. Vallejo
  2. Domínguez-Muñoz, J.E.
Revista:
Medicine: Programa de Formación Médica Continuada Acreditado

ISSN: 0304-5412

Ano de publicación: 2020

Serie: 13

Número: 9

Páxinas: 497-502

Tipo: Artigo

DOI: HTTPS://DOI.ORG/10.1016/J.MED.2020.05.021 DIALNET GOOGLE SCHOLAR

Outras publicacións en: Medicine: Programa de Formación Médica Continuada Acreditado

Resumo

Resumen La patología inflamatoria de la vía biliar hace referencia a un grupo de enfermedades de tipo inflamatorio que afecta a la vía biliar intra y/o extrahepática. La patogenia de estas enfermedades es variable, dependiendo del tipo de enfermedad y estructuras afectas. Los orígenes pueden ser desde una litiasis enclavada hasta una reacción inflamatoria autoinmune. Las manifestaciones clínicas también variarán según la naturaleza de la enfermedad, siendo lo más habitual que se presente dolor en hipocondrio derecho e ictericia, aunque pueden abarcar desde un paciente asintomático con hallazgos analíticos a un paciente con fallo hepático. Los pilares diagnósticos de este tipo de enfermedades son la clínica, las pruebas analíticas y las técnicas de imagen. En ocasiones será necesario también la histología mediante biopsia hepática u otras técnicas. El tratamiento puede variar según el tipo de enfermedad y los síntomas del paciente, abarcando desde el manejo sintomático y el drenaje endoscópico de la vía biliar hasta la cirugía. Inflammatory bile duct disease refers to a group of inflammatory diseases that affect the intrahepatic and extrahepatic bile duct. The pathogenesis of these diseases varies depending on the type of disease and affected structures. The origins can range from an embedded lithiasis to an autoimmune inflammatory reaction. The clinical manifestations also vary according to the nature of the disease, and the most common are pain in the right hypochondrium and jaundice, although the presentation can extend from no symptoms with suggestive laboratory findings to hepatic failure. The diagnostic bases for this type of disease are its symptoms, laboratory tests and imaging techniques. Occasionally, histology through liver biopsy or other techniques might be necessary. The treatment can vary depending on the type of disease and symptoms, encompassing the management of symptoms, endoscopic drainage of the bile duct and surgery.

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