Supramolecular strategies for intracellular delivery and design of new thermoresponsive materials

  1. Fernández Caro, Héctor
unter der Leitung von:
  1. Juan Ramón Granja Guillán Doktorvater
  2. Javier Montenegro García Doktorvater

Universität der Verteidigung: Universidade de Santiago de Compostela

Fecha de defensa: 18 von Dezember von 2020

Gericht:
  1. Ramón Eritja Casadellà Präsident/in
  2. Pablo Alfonso del Pino González de la Higuera Sekretär
  3. Olalla Vázquez Vázquez Vocal
Fachbereiche:
  1. Departamento de Química Orgánica

Art: Dissertation

Teseo: 642000 DIALNET lock_openMINERVA editor

Zusammenfassung

In this Ph.D. dissertation, we have applied supramolecular strategies to promote intracellular delivery of diverse molecules and design potential thermoresponsive systems. Host-guest chemistry has been exploited to encapsulate and deliver different anionic probes such as pyranine, as well as anionic peptides with low self-delivery efficiency. Finally, we have designed potential thermoresponsive supramolecular materials based on self-assembling cyclic peptide nanotubes (SCPNs).