Una revisión de la investigación sobre lenguaje en el deterioro cognitivo leve

  1. Onésimo Juncos-Rabadán 1
  2. Arturo X. Pereiro 1
  3. David Facal 2
  4. Nelly Rodríguez 1
  1. 1 Departamento de Psicología Evolutiva y de la Educación, Facultad de Psicología, Universidad de Santiago de Compostela, A Coruña, España
  2. 2 Fundación Instituto Gerontológico Matia-INGEMA, San Sebastián, España
Revista:
Revista de logopedia, foniatría y audiología

ISSN: 0214-4603

Ano de publicación: 2010

Volume: 30

Número: 2

Páxinas: 73-83

Tipo: Artigo

DOI: 10.1016/S0214-4603(10)70119-4 DIALNET GOOGLE SCHOLAR

Outras publicacións en: Revista de logopedia, foniatría y audiología

Resumo

There are many studies on the neuropsychological profile of mild cognitive impairment (MCI) but the results of investigations specifically addressing its psycholinguistic characteristics have been inconclusive. The present article aims to review the main population-based and experimental studies on language in MCI and to identify the features that help to predict deterioration. Population-based studies have found that the main predictors of MCI and its progression to dementia are measures of verbal fluency, naming and word memory. Experimental studies comparing patients with MCI and matched healthy controls have mainly analyzed performance in different fluency and naming tasks and, to a lesser extent, other dimensions such as comprehension of sentences and texts and production of narrative speech, taking into account its semantic content and syntactic structures. The results of studies seeking neurological correlates of the processes involved in language deterioration in MCI are discussed. The present review highlights the need to explore new linguistic features of MCI, their relationships with other cognitive processes and their psychophysiological bases. The need for interventions to attenuate deterioration and avoid progression to dementia as far as possible is also discussed.

Referencias bibliográficas

  • Albert, M. S., Moss, M. B., Tanzi, R. y Jones, K. (2001). Preclinical prediction of AD using neuropsychological tests. Journal of the International Neuropsychological Society, 7, 631-639.
  • Amiela, A., Jacqmin-Gadda, H., Orgogozo, J. M., Le Carret, N., Helmer, C., Letenneur, L. y cols. (2005). The 9 year cognitive decline before dementia of the Alzheimer type: a prospective population-based study. Brain, 128, 1093-1101.
  • Anstey, K. J., Cherbuin, N., Christensen, H., Burns, R., Reglade-Meslin, C., Salim, A. y cols. (2008). Follow-up of mild cognitive impairment and related disorders over four years in adults in their sixties: the PATH Through Life Study. Dementia and Geria-tric Disorders, 26, 226-233.
  • Apostolova, L. G., Lu, P., Rogers, S., Dutton, R. A., Hayashi, K. M., Toga, A. W. y cols. (2008). 3D mapping of language networks in clinical and pre-clinical Alzheimer’s disease. Brain and Lan-guage, 104, 33-41.
  • Artero, S., Petersen, R., Touchon, J. y Ritchie, K. (2006). Revised criteria for mild cognitive impairment: validation within a longi-tudinal population study. Dementia. Geriatric and Cognitive Dis-orders, 22, 465-470.
  • Bayles, K. A. y Kaszniak, A. W. (1987). Communication and cogni-tion in normal aging and dementia. Boston: College Hill/Litte, Brown and Co.
  • Benedit, M. J. y Alejandre, M. A. (1998). TAVEC: test de aprendizaje verbal España Complutense. Madrid: Tea Ediciones.
  • Blacker, D., Lee, H., Muzikansky, A., Martin, E. C., Tanzi, R., McArdle, J. J. y cols. (2007). Neuropsychological measures in normal individuals that predict subsequent cognitive decline. Archives of Neurology, 64, 862-871.
  • Brayne, C., Huppert, F. A., Xuereb, J. H., Gertz, H. J., Chi, L. Y., McGee, M. A. y cols. (1997). An epidemiological study of the de-mentias in Crambridge. From clinical progression to neuropa-thology. En K. Iqbal, B. Winblad, T. Nishimura, M. Takeda y H. M. Wisniewski (Eds.), Alzheimer’s disease: biology, diagnosis and therapeutics (pp. 11-20). Chichester: Wiley.
  • Bschor, T., Kühl, K. P. y Reischies, F. M. (2001). Spontaneous speech of patients with dementia of the Alzheimer type and mild cognitive impairment. International Psychogeriatrics, 13, 289-298.
  • Cargin, J. W., Maruff, P., Collie, A. y Masters, C. (2006). Mild mem-ory impairment in healthy older adults is disctinct from normal aging. Brain and Cognition, 60, 146-155.
  • Chapman, S. B., Zientz, J., Weiner, M., Rosenberg, R., Frawley, W. y Burns, M. H. (2002). Discourse changes in early Alzheimer disease, mild cognitive impairment, and normal aging. Alzheimer Disease and Associated Disorders, 16, 177-186.
  • Collie, A. y Maruff, P. (2000). The neuropsychology of preclinical Alzheimer’s disease and mild cognitive impairment. Neuro-science and Biobehavioural Reviews, 24, 365-374.
  • Collie, A., Maruff, P., Garby, D. G., Master, C. y Currie J. (2006). The Melbourne Aging Study. En H. A. Tuokko y D.F. Hultsch (Eds.), Mild cognitive impairment. International perspectives (pp. 93-113). Nueva York: Taylor & Francis.
  • Cuetos-Vega, E., Menéndez-González, M. y Calatayud-Nogueira, T. (2007). Descripción de un nuevo test para la detección precoz de la enfermedad de Alzheimer. Revista de Neurología, 44, 469-474.
  • Cullum, S., Huppert, F. A., McGee, M., Dening, T., Ahmed, A., Paykel, E. S. y cols. (2000). Decline across different domains of cognitive functions in normal ageing: results from a longitudinal population-bases study using CAMCOG. International Journal of Geriatric Psychiatry, 15, 853-862.
  • Cunje, A., Molloy, W., Standish, T. I. y Lewis, D. L. (2007). Alternate forms of logical memory and verbal fluency tasks for repeated testing in early cognitive changes. International Psychogeriat-rics, 19, 65-75.
  • Dartigues, J. F., Commenges, D., Letenneur, L., Barberger-Gateau, P., Gilleron, V., Fabrigoule, C. y cols. (1997). Cognitive predictors of dementia in elderly community residents. Neuroepidemiology, 16, 29-39.
  • Dartigues, J. F., Gagnon, M., Barberger-Gateau, P., Letenneur, L., Commenges, D., Sauvel, C. y cols. (1992). The PAQUID Epide-miological Program on brain ageing. Neuroepidemiol, 11 Supl 1, 14-8.
  • Delis, D., Massman, P., Butters, N. y Salmon, D. (1991). Pro les of demented and amnestic patients on the California Verbal Learn-ing Test: implications for the assessment of memory disorders. Psychological Assessment, 3, 19-26.
  • Delis, D. C., Kramer, J. H., Kaplan, E. y Ober, B. A. (1987). Califor-nia Verbal Learning Test: research edition. Nueva York: The Psy-chological Corporation.
  • Díaz, M. C. y Peraita, H. (2008). Detección precoz del deterioro cognitivo ligero de la tercera edad. Psicothema, 20, 438-444.
  • Duong, A., Whitehead, V., Hanratty, K. y Chertkow, H. (2006). The nature of lexico-semantic processing deficits in mild cognitive impairment. Neuropsicología, 44, 1929-1935.
  • Fabrigoule, C., Bareberger-Gateau, F. y Dartigues, J. F. (2006). The PAQUID study. En H. A. Tuokko y D. F. Hultsch (Eds.), Mild cogni-tive impairment. International perspectives (pp. 31-55). Nueva York: Taylor & Francis.
  • Facal, D., González, M. F., Buiza, C., Laskibar, I., Urdaneta, E. y Yanguas, J. J. (2009). Envejecimiento, deterioro cognitivo y len-guaje: resultados del Estudio Longitudinal Donostia. Revista de Logopedia, Foniatría y Audiología, 29, 4-12.
  • Fischer, P., Jungwirth, S., Zehetmayer, S., Weissgram, S., Hoenig-schnabl, S., Gelpi, E. y cols. (2007). Conversion from subtypes of mild cognitive impairment to Alzheimer dementia. Neurology, 68, 288-291.
  • Fleming, J., Matthews, F. E., Chatfield, M. y Brayne, C. (2006). Po-pulation levels of mild cognitive impairment in England and Wales. En H. A. Tuokko y D. F. Hultsch (Eds.), Mild cognitive im-pairment. International perspectives (pp. 77-91). Nueva York: Taylor y Francis.
  • Fleming, V. B. y Harris, J. L. (2008). Complex discourse production in mild cognitive impairment: detecting subtle changes. Apha-siology, 22, 729-740.
  • Flicker, C., Ferris, S. H. y Reisberg, B. (1991). Mild cognitive impair-ment in the elderly: predictors of dementia. Neurology, 41, 1006-1009.
  • Fratiglioni, L., Grut, M., Forsell, Y., Viitanen, M., Grafstrom, M., Colmen, K. y cols. (1991). Prevalence of Alzheimer’s disease and other dementias in an elderly urban population. Relationship with age, sex and education. Neurology, 41, 1886-1892.
  • Graboswky, T. J. y Damasio, A. R. (2000). Investigating language with functional neuroimaging. En A. W. Toga y J. C. Mazziota (Eds.), Brain mapping: the systems (pp. 425-461). Londres: Academic Press.
  • Grober, E., Hall, C. B., Mcginn, M., Nicholls, T., Standford, S., Ehr-lich, A. y cols. (2008). Neuropsychological strategies for detect-ing early dementia. Journal of the International Neuropsychological Society, 14, 130-142.
  • Harris, J. L., Kiran, S., Marquardt, T. P. y Fleming, B. (2008). Communication wellness check-up: age-related changes in commu-nicative abilities. Aphasiology, 22, 813-825.
  • Holtzer, R., Verghese, J., Wang, C., Hall, C. B. y Lipton, R. B. (2008). Within-person across-neuropsychological test variability and incident dementia. JAMA, 300, 823-830.
  • Isaacs, B., Akhtar, A. (1972). The set test: a rapid test of mental function in old people. Age and Aging, 1, 222-226.
  • Juncos-Rabadán, O., Pereiro Rozas, A. X., Álvarez, M. y Facal, D. (2006). Variabilidad en el acceso al léxico en el envejecimiento normal. Revista de Logopedia, Foniatría y Audiología, 26, 132-138.
  • Kaplan, E. F., Goodglass, H. y Weintraub, S. (1983). Boston naming tests. Filadelfia: Lea & Febiger.
  • Katzman, R., Aronson, M., Fuld, P., Kawas, C., Brown, T., Morgen-stern, H. y cols. (1989). Development of dementing illnesses in an 80-year-old volunteer cohort. Ann Neurol, 24, 317-324.
  • Kawas, C., Gray, S., Brookmeyer, R., Fozard, J. y Zonderman, A. (2000). Age-specific incidence rates of Alzheimer’s disease. Neurology, 54, 2072-2077.
  • Kryscio, R. J., Schmitt, F. A., Salazar, J. C., Mendiondo, M. S. y Markesbery, W. R. (2006). Risk factors for transitions from nor-mal to mild cognitive impairment and dementia. Neurology, 66, 828-832.
  • Levelt, W. J. M. (1992). Accessing words in speech production: stag-es, processes and representations. Cognition, 42, 1-22.
  • Levelt, W. J. M., Roelofs, A. y Meyer, A. S. (1999). A theory of lexical access in speech production. Behavioral Brain Sciences, 22, 1-38.
  • López-Higes Sanches, R., Rubio Valdehita, S., Martín Aragoneses, M. T. y Del Río Grande, D. (2008). Variabilidad en la comprensión gramatical en el envejecimiento normal. Revista de Logopedia, Foniatría y Audiología, 28, 15-27.
  • MacKay, D. G. y Burke, D. M. (1990). Cognition and aging: a theory of new learning and the use of old connections. En T. Hess (Ed.), Aging and cognition: knowledge organization and utilization (pp. 281-300). Ámsterdam: North-Holland.
  • Masur, D. M., Sliwinski, M., Lipton R. B., Blau, A. D. y Crystal, H. A. (1994). Neuropsychological prediction of dementia and the absence of dementia in healthy elderly persons. Neurology, 44, 1427-1432.
  • Murphy, K. J., Rich, J. B. y Troyer, A. K. (2006). Verbal  uency pat-terns in amnestic mild cognitive impairment are characteristic of Alzheimer’s type dementia. Journal of the International Neu-ropsychological Society, 12, 570-574.
  • Nutter-Upham, K. E., Saykin, A. J., Rabin, L. A., Roth, R., Wishart, H. A., Pare, L. y cols. (2008). Verbal fluency performance in am-nestic MCI and older adults with cognitive complaints. Archives of Clinical Neuropsychology, 23, 229-241.
  • Ober, B. A. y Shenaut, G. K. (1995). Semantic priming in Alz heimer’s disease: meta-analysis and theoretical evaluation. En P. A. Allen y T. R. Bashore (Eds.), Age differences in word and language processing (pp. 247-271). Ámsterdam: Elsevier.
  • Östberg, P., Fernaeus, S. E., Hellström, A., Bogdanovic, N. y Wahl-und, L. O. (2005). Impaired verb fluency: a sign of mild cognitive impairment. Brain and Language, 95, 273-279.
  • Palmer, K., Bäckman, L., Small, B. J. y Fratiglioni, L (2006). Cogni-tive impairment in elderly person without dementia: findings from the Kungsholmen Project. En H. A. Tuokko y D. F. Hultsch (Eds.), Mild cognitive impairment. International perspectives (pp. 57-75). Nueva York: Taylor y Francis.
  • Perri, R., Carlesimo, G. A., Zannino, G. D., Mauri, M., Muolo, B., Pettenati, C. y cols. (2003). Intentional and automatic measures of specific-category effect in the semantic impairment of patients with Alzheimer’s disease. Neuropsychologia, 41, 1509-1522.
  • Petersen, R. C., Doody, R., Kuzz, A., Mohs, R. C., Morris, J. C., Rotins, P. V. y cols. (2001a). Current concepts in mild cognitive impairment. Archives of Neurology, 58, 1985-1992.
  • Petersen, R. C. y Morris, J. C. (2003). Mild cognitive impairment. Nueva York: Oxford University Press.
  • Petersen, R. C., Smith, G. E., Waring, S. C., Ivnik, R. J., Tangalos, E. G. y Kokmmen, E. (1999). Mild cognitive impairment: clinical characterization and outcome. Archives of Neurology, 56, 303-308.
  • Rami, L., Caprile, C., Gómez-Ansón, B., Sánchez-Valle, R., Monte, G. C., Bosch, B. y cols. (2008). Naming is associated with left temporal pole metabolite levels in neurodegenerative diseases. Dementia and Geriatric Cognitive Disorders, 25, 212-217.
  • Rey, A. (1964). L’examen clinique en psychologie. París: Presses Uni-versitaires de France.Ribeiro, F., De Mendoça, A. y Guerreiro, M. (2006). Mild cognitive impairment: deficits in cognitive domains other than memory. Dementia and Geriatric Cognitive Disorders, 21, 284-290.
  • Ribeiro, F., Guerreiro, M. y De Mendoça, A. (2007). Verbal learn-ing and memory deficits in mild cognitive impairment. Jour-nal of Clinical and Experimental Neuropsychology, 29, 187-197.
  • Ritchie, K., Artero, S. y Touchon, J. (2001). Classification criteria for mild cognitive impairment: a population-based validation study. Neurology, 56, 37-42.
  • Roark, B., Mitchell, M. y Hollingshead, K. (2007). Syntactic com-plexity measures for detecting mild cognitive impairment. En Proceedings of the ACL 2007 Workshop on Biomedical Natural Language Processing (BioNLP) (pp. 1-8).
  • Roberts, R. O., Geda, Y. E., Knopman, D. S., Cha, R. H., Pankratz, S., Boeve, B. F. y cols. (2008). The Mayo Clinic Study of aging: design and sampling, participation, baseline measures and sam-ple characteristics. Neuroepidemiology, 30, 58-69.
  • Rodríguez, N., Juncos-Rabadán, O. y Facal, D. (2008). El fenómeno de la punta de la lengua en el deterioro cognitivo leve. Un estudio piloto. Revista de Logopedia, Foniatría y Audiología, 28, 28-33.
  • Schmitt, F. A., Davis, D. G., Wekstein, D. R., Smith, C. D., Ashford J. W. y Markesbery, W. R. (2000). “Preclinical” AD revisited. Neuropa-thology of cognitively normal older adults. Neurology, 55, 370-376.
  • Seidenber, M., Guidotti, L., Nielson, K. A., Woodard, J. L., Durgeri-an, S., Zhan, Q. y cols. (2009). Semantic knowledge for famous names in mild cognitive impairment. Journal of the Internation-al Neuropsychology Society, 15, 9-18.
  • Smith, G., Ivnik, R., Malec, J., Petersen, R., Tangalos, E. y Kurland, L. (1992). Mayo’s Older Americans Normative Studies (MOANS): factor structure of a core batery. Psychological Assessment: A Journal of Consulting and Clinical Psychology, 4, 382-390.
  • Smith, G., Machulda, M. y Kantarci, K. (2006). A perspective from the Mayo Clinic. En H. A. Tuokko y D. F. Hultsch (Eds.). Mild cog-nitive impairment. International perspectives (pp. 131-162). Nueva York: Taylor & Francis.
  • Tabert, M. H., Manly, J. J., Liu, X., Pelton, G. H., Sosenblum, S., Jacobs, M. y cols. (2006). Neuropsychological prediction of con-version to Alzheimer disease in patients with mild cognitive im-pairment. Archives of General Psychiatry, 63, 916-20.
  • Taler, V. y Philips, N. A. (2008). Language performance in Alzheim-er’s disease and mild cognitive impairment: a comparative re-view. Journal of Clinical and Experimental Neuropsychology, 30, 501-556.
  • Testa, J. E., Ivnik, R. J., Boeve, B., Petersen, R. C., Pankratz, V. S., Knopman, D. y cols. (2004). Confrontation naming does not add incremental diagnostic utility in MCI and Alzheimer’s disease. Journal of the International Neuropsychological Society, 10, 504-512.
  • Tierney, M. C. (2006). Prediction of probable Alzheimer’s disease: the Sunnybrook Memory Study. En H. A. Tuokko y D. F. Hultsch (Eds.). Mild cognitive impairment. International perspectives (pp. 162-180). Nueva York: Taylor & Francis.
  • Tierney, M. C, Yao, C., Kiss, A. y McDowell, I. (2005). Neuropsycho-logical tests accurately predict incident Alzheimer’s disease after five and ten years. Neurology, 64, 1853-1859.
  • Tiraboschi, P., Hansen, L., Thal, L. y Corey-Bloom, J. (2004). The importance of neuritic plaques and tangles to development and evolution of AD. Neurology, 62, 1984-1989.
  • Troyer, A. K., y Moscovitch, M. (2006). Cognitive processes of verbal fluency tests. En A. Poreh (Ed.), The quantified processes approach to neuropschychological assessment (pp. 185-202). Nueva York: Psychology Press.
  • Vandenbulcke, M., Peeters, R., Dupont, P., Van Hecke, P. y Vanden-berghe, R. (2007). Word reading and posterior temporal dysfunc-tion in amnestic mild cognitive impairment. Cerebral Cortex, 17, 542-552.
  • Wilson, R. S., Aggarwal, N. T. y Bennett, D. (2006). Mild cognitive impairment in the Religious Orders Study. En H. A. Tuokko, y D. F. Hultsch (Eds.). Mild cognitive impairment. International per-spectives (pp. 117-130). Nueva York: Taylor & Francis.
  • Wilson, R. S., Beckett, L. A., Barnes, L. L., Schneider, J. A., Bach, J., Evans, D. A. y cols. (2002). Individual difference in rates of change in cognitive abilities of older persons. Psychology and Aging, 17, 179-193.
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