Biomarcadores en el queratocono
- MI. Lema Gesto 123
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1
Universidade de Santiago de Compostela
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2
Instituto de Investigación Sanitaria de Santiago de Compostela
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Instituto de Investigación Sanitaria de Santiago de Compostela
Santiago de Compostela, España
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3
Complexo Hospitalario Universitario de Santiago
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Complexo Hospitalario Universitario de Santiago
Santiago de Compostela, España
ISSN: 1133-7737
Year of publication: 2019
Volume: 27
Issue: 4
Pages: 224-228
Type: Article
More publications in: Annals d'oftalmologia: òrgan de les Societats d'Oftalmologia de Catalunya, Valencia i Balears
Abstract
The most important utility of a biomarker is for early diagnosis. For this it is necessary to know the protein expression profile in physiological and pathological conditions. The best biomarkers are proteins: they can detect disease, activity, prognosis and therapeutic response. In keratoconus, biomarkers can be determined in tears, in blood cells and in corneal and conjunctival epithelial cells. The combination of all of them is crucial to know the physiopathology of ectasia and a great help for early diagnosis and monitoring of the disease.