Biomarcadores en el queratocono

  1. MI. Lema Gesto 123
  1. 1 Universidade de Santiago de Compostela
    info

    Universidade de Santiago de Compostela

    Santiago de Compostela, España

    ROR https://ror.org/030eybx10

  2. 2 Instituto de Investigación Sanitaria de Santiago de Compostela
    info

    Instituto de Investigación Sanitaria de Santiago de Compostela

    Santiago de Compostela, España

  3. 3 Complexo Hospitalario Universitario de Santiago
    info

    Complexo Hospitalario Universitario de Santiago

    Santiago de Compostela, España

    ROR https://ror.org/00mpdg388

Journal:
Annals d'oftalmologia: òrgan de les Societats d'Oftalmologia de Catalunya, Valencia i Balears

ISSN: 1133-7737

Year of publication: 2019

Volume: 27

Issue: 4

Pages: 224-228

Type: Article

More publications in: Annals d'oftalmologia: òrgan de les Societats d'Oftalmologia de Catalunya, Valencia i Balears

Abstract

The most important utility of a biomarker is for early diagnosis. For this it is necessary to know the protein expression profile in physiological and pathological conditions. The best biomarkers are proteins: they can detect disease, activity, prognosis and therapeutic response. In keratoconus, biomarkers can be determined in tears, in blood cells and in corneal and conjunctival epithelial cells. The combination of all of them is crucial to know the physiopathology of ectasia and a great help for early diagnosis and monitoring of the disease.