COPD and lung cancerunderdiagnosis and clinical characterization

  1. MOURONTE ROIBAS, CECILIA
Supervised by:
  1. Alberto Ruano Raviña Director
  2. Virginia Leiro Fernández Co-director
  3. Alberto Fernández Villar Co-director

Defence university: Universidade de Santiago de Compostela

Fecha de defensa: 23 May 2019

Committee:
  1. Julio Ancochea Bermúdez Chair
  2. Agustín Montes Martínez Secretary
  3. Carmen Diego Roza Committee member
Department:
  1. Department of Psychiatry, Radiology, Public Health, Nursing and Medicine

Type: Thesis

Teseo: 590093 DIALNET lock_openMINERVA editor

Abstract

Both COPD and LC share some common features, such as their high mortality and common risk factors as tobacco history, genetic background, environmental exposure and similar underlying pathogenic mechanisms. The aim of this project is to establish COPD prevalence, as well as its underdiagnosis in LC patients, and to analyze their clinical profile, comparing it with a control group of patients with COPD and no LC, evaluating different phenotypes and looking for biomarkers with potential at early diagnosis of LC or even with therapeutic and prognostic implications in this subset of patients. This work contains four different studies: a systematic review, a prospective cohort study based on patients with LC with/without COPD, and two case-control study with subjects with COPD with/without LC.