Oral mucosal peeling related to dentifrices and mouthwashesa systematic review

  1. Daniel Pérez López 1
  2. Pablo Ignacio Varela Centelles 2
  3. María José García Pola 3
  4. Pablo Castelo Baz 1
  5. Lucía García-Caballero Pérez 1
  6. Juan M. Seoane Romero 3
  1. 1 Dept of Surgery & Medical-Surgical Specialities. School of Medicine & Dentristry. University of Santiago de Compostela
  2. 2 Dept of Surgery & Medical-Surgical Specialities. School of Medicine & Dentristry. University of Santiago de Compostela; CS Praza do Ferrol. EOXI Lugo, Cervo, e Monforte. Servizo Galego de Saúde. Lugo. Spain
  3. 3 Dept of Surgery & Medical-Surgical Specialities. School of Medicine & Health Sciences. University of Oviedo. Spain
Revista:
Medicina oral, patología oral y cirugía bucal. Ed. inglesa

ISSN: 1698-6946

Ano de publicación: 2019

Volume: 24

Número: 4

Páxinas: 15

Tipo: Artigo

DOI: 10.4317/MEDORAL.22939 DIALNET GOOGLE SCHOLAR lock_openAcceso aberto editor

Outras publicacións en: Medicina oral, patología oral y cirugía bucal. Ed. inglesa

Obxectivos de Desenvolvemento Sustentable

Resumo

The aim of this systematic review was to summarise the clinical information available about oral mucosal peeling (OMP) and to explore its aetiopathogenic association with dentifrices and mouthwashes. PICOS outline: Population: subjects diagnosed clinically and/or pathologically. Intervention: exposition to oral hygiene products. Comparisons: patients using products at different concentrations. Outcomes: clinicopathological outcomes (primary) and oral epithelial desquamation (secondary) after use. Study design: any. Exclusion criteria: reports on secondary or unpublished data, in vitro studies. Data were independently extracted by two reviewers. Fifteen reports were selected from 410 identified. Descriptive studies mainly showed low bias risk, experimental studies mostly an “unclear risk”. Dentifrices or mouthwashes were linked to OMP, with an unknown origin in 5 subjects. Sodium lauryl-sulphate (SLS) was behind this disorder in 21 subjects, tartar-control dentifrices in 2, and flavouring agents in 1 case. Desquamation extension was linked to SLS concentration. Most cases were painless, leaving normal mucosa after desquamation. Tartar-control dentifrices caused ulcerations more frequently. OMP management should consider differential diagnosis with oral desquamative lesions, particularly desquamative gingivitis, with a guided clinical interview together with pathological confirmation while discouraging the use of the product responsible for OMP.

Referencias bibliográficas

  • Stec, IP. (1972). A possible relationship between desquamation and dentifrices. A clinical study. J Am Dent Hyg Assoc. 46. 42
  • Berton, F,Stacchi, C,Bussani, R,Berton, T,Lombardi, T,Di Lenarda, R. (2017). Toothpaste-Induced Oral Mucosal Desquamation. Dermatitis. 28. 162
  • Plonait, DR,Reichart, PA. (1999). Epitheliolysis of the mouth mucosa (mucosal peeling) as a side effect of toothpaste. Mund Kiefer Gesichtschir. 3. 78-81
  • Zegarelli, DJ,Silvers, DN. (1994). Shedding oral mucosa. Cutis. 54. 323
  • DeLattre, VF. (1999). Factors contributing to adverse soft tissue reactions due to the use of tartar control toothpastes: report of a case and literature review. J Periodontol. 70. 803
  • Kuttan, NA,Narayana, N,Moghadam, BK. (2001). Desquamative stomatitis associated with routine use of oral health care products. Gen Dent. 49. 596-602
  • Skaare, A,Eide, G,Herlofson, B,Barkvoll, P. (1996). The effect of toothpaste containing triclosan on oral mucosal desquamation. A model study. J Clin Periodontol. 23. 1100
  • Searls, JC,Berg, CA. (1986). The influence of dentifrice detergents on oral epithelial slough. Dent Hyg (Chic). 60. 20
  • Gotze, W. (1977). The effect of toothpaste on the gingiva. Dtsch Zahnarztl Z. 32. 448
  • Jacoby, LF,Thor, G,Lange, DE. (1975). Comparative clinical and cytological studies following the use of 2 toothpastes. Dtsch Zahnarztl Z. 30. 385
  • Rubright, WC,Walker, JA,Karlsson, UL,Diehl, DL. (1978). Oral slough caused by dentifrice detergents and aggravated by drugs with antisialic activity. J Am Dent Assoc. 97. 215
  • Rhein, LD,Simion, FA,Hill, RL,Cagan, RH,Mattai, J,Maibach, HI. (1990). Human cutaneous response to a mixed surfactant system: role of solution phenomena in controlling surfactant irritation. Dermatologica. 180. 18-23
  • Helenius, A,Simons, K. (1975). Solubilization of membranes by detergents. Biochim Biophys Acta. 415. 29-79
  • Imokawa, G. (1980). Comparative study on the mechanism of irritation by sulfate and phosphate type of anionic surfactants. J Soc Cosmet Chem. 31. 45-66
  • Ernst, R. (1980). Surface active betaines as protective agents against denaturation of an enzyme by alkyl sulphate detergents. American Oil Chem Soc. 57. 93
  • Hassona, Y,Scully, C. (2013). Oral mucosal peeling. Br Dent J. 214. 374
  • Maderal, AD,Lee Salisbury, P3rd,Jorizzo, JL. (2018). Desquamative gingivitis: Clinical findings and diseases. J Am Acad Dermatol. 78. 839-848
  • (2015). Centre for Reviews and Dissemination. United Kingdom.
  • Shamseer, L,Moher, D,Clarke, M,Ghersi, D,Liberati, A,Petticrew, M. (2015). Preferred reporting items for systematic review and meta-analysis protocols (PRISMA-P) 2015: elaboration and explanation. BMJ. 350. 7647
  • Saaiq, M,Ashraf, B. (2017). Modifying "Pico" Question into "Picos" Model for More Robust and Reproducible Presentation of the Methodology Employed in A Scientific Study. World J Plast Surg. 6. 390
  • Herlofson, BB,Barkvoll, P. (1993). Desquamative effect of sodium lauryl sulfate on oral mucosa. A preliminary study. Acta Odontol Scand. 51. 39-43
  • Higgins, JP,Altman, DG,Gotzsche, PC,et, al. (2011). The Cochrane Collaboration's tool for assessing risk of bias in randomised trials. BMJ. 343. 5928
  • Murad, MH,Sultan, S,Haffar, S,Bazerbachi, F. (2018). Methodological quality and synthesis of case series and case reports. BMJ Evid Based Med. 23. 60
  • Young, HM,Levy, RM. (1987). A case report: adverse reaction to a new dentifrice. Fla Dent J. 58. 20
  • Macdonald, JB,Tobin, CA,Hurley, MY. (2016). Oral leukoedema with mucosal desquamation caused by toothpaste containing sodium lauryl sulphate. Cutis. 97. 4-5
  • Kowitz, G,Lucatorto, F,Bennett, W. (1973). Effects of dentifrices on soft tissues of the oral cavity. J Oral Med. 28. 105
  • Kowitz, G,Jacobson, J,Meng, Z,Lucatorto, F. (1990). The effects of tartar-control toothpaste on the oral soft tissues. Oral Surg Oral Med Oral Pathol. 70. 529
  • Fischman, SL,Aguirre, A,Charles, CH. (2004). Use of essential oil-containing mouthrinses by xerostomic individuals: determination of potential for oral mucosal irritation. Am J Dent. 17. 23
  • Herlofson, BB,Barkvoll, P. (1996). Oral mucosal desquamation caused by two toothpaste detergents in an experimental model. Eur J Oral Sci. 104. 21
  • Barkvoll, P,Rolla, G,Svendsen, K. (1989). Interaction between chlorhexidine digluconate and sodium lauryl sulfate in vivo. J Clin Periodontol. 16. 593
  • Fakhry-Smith, S,Din, C,Nathoo, SA,Gaffar, A. (1997). Clearance of sodium lauryl sulphate from the oral cavity. J Clin Periodontol. 24. 313
  • Kjaerheim, V,Barkvoll, P,Waaler, SM,Rolla, G. (1995). Triclosan inhibits histamine-induced inflammation in human skin. J Clin Periodontol. 22. 423
  • Bettger, WJ,O'Dell, BL. (1981). A critical physiological role of zinc in the structure and function of biomembranes. Life Sci. 28. 1425
  • Herlofson, BB,Barkvoll, P. (1996). Oral mucosal desquamation of pre- and post-menopausal women. A comparison of response to sodium lauryl sulphate in toothpastes. J Clin Periodontol. 23. 567
  • Endo, H,Rees, TD, Allen, EP, Kuyama, K, Aoki, S, Yamamoto, H. (2014). A stab-and-roll biopsy technique to maintain gingival epithelium for desquamative gingivitis. J Periodontol. 85. 802
  • Ricotti, C,Kowalczyk, J,Fernandez, A,Nousari, CH. (2008). Mucosal "peeling" biopsy technique for the immunopathologic evaluation of desquamative gingivitis-associated mucous membrane pemphigoid. Arch Dermatol. 144. 1538
  • Lo Russo, L,Fedele, S, Guiglia, R, Ciavarella, D, Lo Muzio, L, Gallo, P. (2008). Diagnostic pathways and clinical significance of desquamative gingivitis. J Periodontol. 79. 4-24
  • Lo Russo, L,Fierro, G, Guiglia, R, Compilato, D, Testa, NF, Lo Muzio, L. (2009). Epidemiology of desquamative gingivitis: evaluation of 125 patients and review of the literature. Int J Dermatol. 48. 1049