Conformationally constrained butyrophenones with mixed dopaminergic (D2) and serotoninergic (5-HT2(A), 5-HT2(C)) affinities: Synthesis, pharmacology, 3D-QSAR, and molecular modeling of (aminoalkyl)benzo- and - thienocycloalkanones as putative atypical antipsychotics

  1. Raviña, E.
  2. Negreira, J.
  3. Cid, J.
  4. Masaguer, C.F.
  5. Rosa, E.
  6. Rivas, M.E.
  7. Fontenla, J.A.
  8. Loza, M.I.
  9. Tristán, H.
  10. Cadavid, M.I.
  11. Sanz, F.
  12. Lozoya, E.
  13. Carotti, A.
  14. Carrieri, A.
Journal:
Journal of Medicinal Chemistry

ISSN: 0022-2623

Year of publication: 1999

Volume: 42

Issue: 15

Pages: 2774-2797

Type: Article

DOI: 10.1021/JM981094E GOOGLE SCHOLAR