Riesgo de exposición a Fasciola hepática en ganado vacuno en extensivo de Uruguay y Portugal determinado mediante ELISA y un antígeno recombinante

  1. J Sanchís 1
  2. GV Hillyer 2
  3. LM Madeira de Carvalho 3
  4. MI Macchi 4
  5. C Gomes 3
  6. G Maldini 4
  7. G Stilwell 3
  8. JM Venzal 4
  9. A Paz-Silva 1
  10. R Sánchez-Andrade 1
  11. MS Arias 1
  1. 1 Universidad de Santiago de Compostela Facultad de Veterinaria Departamento Patología Animal, Epidemiología, Zoonosis y Enfermedades Parasitarias
  2. 2 Universidad de Puerto Rico Campus de Ciencias Médicas Escuela de Medicina
  3. 3 Universidad Técnica de Lisboa Facultad de Medicina Veterinaria Centre for Interdisciplinary Research in Animal Health
  4. 4 Universidad de la República Parasitología
Show affiliations +
Journal:
Archivos de Medicina Veterinaria

ISSN: 0301-732X,  0717-6201

Year of publication: 2015

Volume: 47

Issue: 2

Pages: 201-208

Type: Article

DOI: 10.4067/S0301-732X2015000200011 DIALNET GOOGLE SCHOLAR lock_openOpen access editor

More publications in: Archivos de Medicina Veterinaria

Abstract

The risk of exposure to Fasciola hepatica in cattle maintained under extensive conditions from two different climatic areas was evaluated. Bovine serum samples collected in Uruguay (humid subtropical climate; 1,192 samples) and Portugal (mediterranean climate; 473 samples) were tested against a F. hepatica recombinant surface antigen (FhrAPS) by means of an ELISA. Data obtained was analyzed according to the bovine breed, age and aptitude. An overall percentage of 56% (95% CI, 53-59) cattle were positive to the FhrAPS-ELISA in Uruguay, with significantly highest percentages in 2-4 year Holstein dairy cows. In Portugal, the percentage of sensitization was 47% (95% CI, 43-52) with the highest values recorded among Crossbreeds and beef bovines between 2-4 years of age. By means of the FhrAPS-ELISA, it was concluded the risk of exposure to F. hepatica among extensively reared cattle is higher in areas under humid subtropical climate than in those with Mediterranean climate. Calves are at higher risk of being exposed to the liver trematode independent of the climate conditions which emphasises the need for preventive measures against infective stages found in the environment and combne them with successful deworming programs.

Bibliographic References

  • Alcaíno, H,Apt, W. (1989). Algunos antecedentes sobre la fasciolosis animal y humana. Monografías Medicina Veterinaria. 11. 14-29
  • Arias, MS,Suárez, JL,Hillyer, GV,Francisco, I,Calvo, E,Sánchez-Andrade, R,Díaz, P,Francisco, R,Díez-Baños, P,Morrondo, P,Paz-Silva, A. (2009). A recombinant-based ELISA evaluating the efficacy of netobimin and albendazole in ruminants with naturally acquired fascioliasis. Vet J. 182. 73-78
  • Arias, M,Piñeiro, P,Hillyer, GV,Suárez, JL,Francisco, I,Cortiñas, FJ,Díez-Baños, P,Morrondo, P,Sánchez-Andrade, R,Paz-Silva, A. (2010). An approach of the laboratory to the field: assessment of the influence of cattle management on the seroprevalence of fascioliasis by using polyclonal- and recombinant-based ELISAs. J Parasitol. 96. 626-631
  • Arias, M,Lomba, C,Dacal, V,Vázquez, L,Pedreira, J,Francisco, I,Piñeiro, P,Suárez, JL,Díez-Baños, P,Morrondo, P,Sánchez-Andrade, R,Paz-Silva, A. (2011). Prevalence of mixed trematode infections in an abattoir receiving cattle from northern Portugal and north-west Spain. Vet Rec. 168. 408-413
  • Arias, M,Cazapal-Monteiro, CF,Suárez, J,Miguélez, S,Francisco, I,Suárez, JL,Paz-Silva, A,Sánchez-Andrade, R,Mendoza deGives, P. (2013). A preliminary analysis of the mixed production of spores of filamentous fungi for preventing soil-transmitted helminthzoonoses. Biomed Res Int.
  • Bennema, SC,Ducheyne, E,Vercruysse, J,Claerebout, E,Hendrickx, G,Charlier, J. (2011). Relative importance of management, meteorological and environmental factors in the spatial distribution of Fasciola hepatica in dairy cattle in a temperate climate zone. Int J Parasitol. 41. 225-233
  • Carámbula, M. (1996). Pasturas naturales mejoradas. Editorial Hemisferio Sur. Montevideo.
  • Carnevale, S,Rodríguez, MI,Guarnera, EA,Carmona, C,Tanos, T,Ángel, SO. (2001). Immunodiagnosis of fasciolosis using recombinant procathepsin L cystein proteinase. Diagn Microbiol Infect Dis. 41. 43-49
  • Castro, L,Brito, G. (2008). Auditoría de Calidad de Carne Vacuna 2007-2008. 5 Congreso de Producción, Industrialización y Comercialización de Carne "Del Campo al Plato".
  • Chauvin, A,Bouvet, G,Boulard, C. (1995). Humoral and cellular immune responses to Fasciola hepatica experimental primary and secondary infection in sheep. Int J Parasitol. 25. 1227-1241
  • Conceição, MA,Durão, RM,Costa, IM,Costa, JM da. (2002). Evaluation of a simple sedimentation method (modified McMaster) for diagnosis of bovine fascioliosis. Vet Parasitol. 105. 337-343
  • Conceição, MA,Durão, RM,Costa, IM,Castro, A,Louzã, AC,Costa, JC. (2004). Herd-level seroprevalence of fasciolosis in cattle in north central Portugal. Vet Parasitol. 123. 93-103
  • Cornelissen, JB,Gaasenbeek, CP,Borgsteede, FH,Holland, WG,Harmsen, MM,Boersma, WJ. (2001). Early immunodiagnosis of fasciolosis in ruminants using recombinant Fasciola hepatica cathepsin L-like protease. Int J Parasitol. 31. 728-737
  • Dias, AS,Araújo, JV,Braga, FR,Araújo, JM,Puppin, AC,Fernandes, FM,Ramos, RF,Bertonceli, RM,Silva, RG da,Perboni, WR. (2012). Biological control of Fasciola hepatica eggs with the Pochonia chlamydosporia fungus after passing through the cattle gastrointestinal tract. Parasitol Res. 110. 663-667
  • Dunkel, AM,Rognlie, MC,Johnson, GR,Knapp, SE. (1996). Distribution of potential intermediate hosts for Fasciola hepatica and Fascioloides magna in Montana, USA. Vet Parasitol. 62. 63-70
  • Eleftheratos, K,Tselioudis, G,Zerefos, C,Nastos, P,Douvis, C,Kapsomenakis, I. (2011). Observed and predicted climate changes in Uruguay and adjacent areas. Hell J Geosci. 45. 83-90
  • Fox, NJ,White, PC,McClean, CJ,Marion, G,Evans, A,Hutchings, MR. (2011). Predicting impacts of climate change on Fasciola hepatica risk. PLoS One. 6. 16126
  • Greiner, M,Gardner, IA. (2000). Application of diagnostic tests in veterinary epidemiologic studies. Prev Vet Med. 45. 43-59
  • Hope Cawdery, MJ. (1984). Review of economic importance of fascioliasis in sheep and cattle. Irish Vet. 3. 14-22
  • Ibarra, F,Montenegro, N,Vera, Y,Boulard, CH,Quiroz, H,Flores, J,Ochoa, P. (1998). Comparison of three ELISA tests for seropidemiology of bovine fasciolosis. Vet Parasitol. 77. 229-236
  • (2012). INE. Instituto Nacional de Estatística 2011.
  • Kottek, M,Grieser, J,Beck, C,Rudolf, B,Rubel, F. (2006). World map of the Köppen-Geiger climate classification updated. Meteorol Z. 15. 259-263
  • Kuchai, JA,Chishti, MZ,Zaki, MM,Muzaffar Rasool, MAD,Ahmad, J,Tak, H. (2011). Epidemiological aspects of fascioliasis among cattle of Ladakh. Global Vet. 7. 342-346
  • Kuerpick, B,Fiedor, C,von Samson-Himmelstjerna, G,Schnieder, T,Strube, C. (2012). Bulk milk-estimated seroprevalence of Fasciola hepatica in dairy herds and collecting of risk factor data in East Frisia, northern Germany. Berl Munch Tierarztl. 125. 345-350
  • Luzón-Peña, M,Rojo-Vázquez, FA,Gómez-Bautista, M. (1995). Seasonal availability of Fasciola hepatica metacercariae in a temperate Mediterranean area (Madrid, Spain). Zbl Vet Med B. 42. 577-585
  • (1986). MAFF, Ministry of Agriculture, Fisheries and Food Manual of veterinary parasithological laboratory techniques. HMSO. London.
  • Marcos, LA,Terashima, A,Leguía, G,Canales, M,Espinoza, JR,Gotuzzo, E. (2007). Fasciola hepatica infection in Peru: An emergent disease. Rev Gastroenterol Perú. 27. 389-396
  • Marley, SE,Corwin, RM,Hutcheson, DP. (1996). Effect of Fasciola hepatica on productivity of beef steers from pasture through feedlot. Agri-Practice. 17. 18-23
  • Mezo, M,González-Warleta, M,Castro-Hermida, JA,Muiño, L,Ubeira, FM. (2011). Association between anti-F. hepatica antibody levels in milk and production losses in dairy cows. Vet Parasitol. 180. 237-242
  • Nari, A,Cardozo, H,Solari, MA,Petraccia, C,Acosta, D. (1986). Estudio preliminar sobre el desarrollo de Limnaea viatrix D'Orbigny (1835) en condiciones controladas de temperatura y humedad. Veterinaria. 22. 13-17
  • Oldham, G. (1982). Antibody responses to Fasciola hepatica antigens during liver fluke infection of cattle. Curr Top Vet Med Anim Sci. 22. 57-82
  • (1997). Organización Mundial de la Salud Vector control: Methods for use by individuals and communities. World Health Organization. Geneva.
  • Otranto, D,Traversa, D. (2003). Dicrocoeliosis of ruminants: a little known fluke disease. Trends Parasitol. 19. 12-15
  • Paz-Silva, A,Sánchez-Andrade, R,Suárez, JL,Pedreira, J,Arias, M,López, C,Panadero, R,Díaz, P,Díez-Baños, P,Morrondo, P. (2003). Prevalence of natural ovine fasciolosis shown by demostrating the presence of serum circulating antigens. Parasitol Res. 91. 328-331
  • Paz-Silva, A,Hillyer, GV,Sánchez-Andrade, R,Rodríguez-Medina, JR,Arias, M,Morrondo, P,Díez-Baños, P. (2005). Isolation, identification and expression of a Fasciola hepatica cDNA encoding a 2.9-kDa recombinant protein for the diagnosis of ovine fasciolosis. Parasitol Res. 95. 129-135
  • Paz-Silva, A,Hillyer, GV,Arias, MS,Sánchez-Andrade, R,Pedreira, J,Suárez, JL,Lomba, C,Díaz, P,Francisco, I,Díez-Baños, P,Morrondo, P. (2007). A cross-sectional study of fascioliasis in autochthonous cattle from NW Spain by using a 2.9-kDa recombinant protein. Int J Appl Res Vet M. 5. 52-56
  • Rapsch, C,Schweizer, G,Grimm, F,Kohler, L,Bauer, C,Deplazes, P,Braun, U,Torgerson, PR. (2006). Estimating the true prevalence of Fasciola hepatica in cattle slaughtered in Switzerland in the absence of an absolute diagnostic test. Int J Parasitol. 36. 1153-1158
  • Reid, JFS,Dargie, JD. (1995). Como os estágios adultos de Fasciola hepatica afetam a saúde e a produtividade do bovino. Hora Vet. 15. 23-26
  • Rodríguez, DC,Pino, N,Peñuela, G. (2012). Microbiological quality indicators in waters of dairy farms: detection of pathogens by PCR in real time. Sci Total Environ. 427428. 314-318
  • Rojo, FA,Ferre, I. (1999). Parasitología Veterinaria. McGraw-Hill-Interamericana. Madrid.
  • Salimi-Bejestani, MR,Cripps, P,Williams, DJ. (2008). Evaluation of an ELISA to assess the intensity of Fasciola hepatica infection in cattle. Vet Rec. 162. 109-111
  • Paz-Silva, A,Suárez, JL,Panadero, R,Díez.-Baños, P,Morrondo, P. (2000). Use of a sandwich-enzyme-linked immunosorbent assay (SEA) for the diagnosis of natural Fasciola hepatica infection in cattle from Galicia (NW Spain). Vet Parasitol. 93. 39-46
  • Sánchez-Andrade, R,Paz-Silva, A,Suárez, JL,Panadero, R,Pedreira, J,López, C,Díez-Baños, P,Morrondo, P. (2002). Influence of age and breed on natural bovine fasciolosis in an endemic area (Galicia, NW Spain). Vet Res Commun. 26. 361-370
  • Sanchís, J,Miguélez, S,Solari, MA,Piñeiro, P,Macchi, MI,Maldini, G,Venzal, J,Morrondo, P,Díez-Baños, P,Sánchez-Andrade, R,Paz-Silva, A,Arias, MS. (2011). Seroprevalencia de la fasciolosis bovina en el departamento de Salto (Uruguay). Rev Ibero-Latin Parasitol. 70. 163-171
  • Sariözkan, S,Yalcin, C. (2011). Estimating the total cost of bovine fasciolosis in Turkey. Ann Trop Med Parasitol. 105. 439-444
  • Schweizer, G,Braun, U,Deplazes, P,Torgerson, PR. (2005). Estimating the financial losses due to bovine fasciolosis in Switzerland. Vet Rec. 157. 188-193
  • Sen, M,Yildirim, A,Bi§kin, Z,Düzlü, O,Inci, A. (2011). The investigation of fasciolosis in cattle by copro-ELISA and stool examination techniques around the Derinkuyu region. Türkiye Parazitol Derg. 35. 81-85
  • Thrusfield, M. (2005). Veterinary epidemiology. 3. Blackwell. Oxford.
Data source: Dialnet