Efecto de la instilación del colicursi® anestésico doble (tetracaína 0,1% y oxibuprocaína 0,4%) sobre el espesor corneal central y paracentral

  1. J.A. Díaz-Rey
  2. M.J. Giráldez
  3. C. García-Resúa
  4. E. Yebra-Pimentel
Journal:
Archivos de la Sociedad Española de Oftalmologia

ISSN: 0365-6691

Year of publication: 2009

Volume: 84

Issue: 1

Pages: 23-30

Type: Article

DOI: 10.4321/S0365-66912009000100004 DIALNET GOOGLE SCHOLAR lock_openOpen access editor

More publications in: Archivos de la Sociedad Española de Oftalmologia

Abstract

Objective: To study the effect of 1 drop of combined topical anaesthesia (tetracaine 0.1% and oxybuprocaine 0.4%) on central corneal thickness (CCT) values and at 2.5 mm from the corneal centre in nasal, temporal, superior and inferior hemi meridians, monitored by Orbscan over a period of 16 minutes. Materials and methods: The corneal thickness of 12 right eyes of 12 young healthy men was determined using the Orbscan Topography System. Values were determined at the centre and paracentral regions 2.5 mm from the centre every 2 minutes for 16 minutes before and after the administration of 1 drop of double anaesthetic Colircusi® which contains tetracaine 0.1% and oxybuprocaine 0.4%. Results: There was no obvious trend of central and paracentral corneal thickness value change before and after administration of Colircusi® (paired ANOVA, p>0.05). Although corneal thickness variation was not statistically significant, higher differences were observed at the 6 minute time-point for CCT and at 8 minutes for nasal paracentral corneal thickness. Conclusions: One drop of double anaesthetic Colircusi® with tetracaine 0.1% and oxibuprocaine 0.4% does not produce any significant change in central corneal thickness or in paracentral regions 2.5 mm from the centre (nasal, temporal, superior and inferior hemi meridians).

Bibliographic References

  • Doughty, MJ, Zaman, ML. (2000). Human corneal thickness and its impact on intraocular pressure measures: a review and meta-analysis approach. Surv Ophthalmol. 44. 367-408
  • Herse, P, Siu, A. (1992). Short-term effects of proparacaine on human corneal thickness. Acta Ophthalmol (Copenh). 70. 740-744
  • Díaz Alemán, VT, Fernández-Baca Vaca, G, Abreu González, R, Díaz-Flores Varela, L, Muiños Gómez-Camacho, JA, Aguilar Estévez, JJ. (2003). Estudio comparativo de dos sistemas de paquimetría: Efecto de las gotas anestésicas sobre el espesor corneal. Arch Soc Canar Oftal. 14. 7-10
  • Nam, SM, Lee, HK, Kim, EK, Seo, KY. (2006). Comparison of corneal thickness after the instillation of topical anesthetics: proparacaine versus oxybuprocaine. Cornea. 25. 51-54
  • Lam, AK, Chen, D. (2007). Effect of proparacaine on central corneal thickness values: an evaluation using noncontact specular microscopy and pentacam. Cornea. 26. 55-58
  • Asensio, I, Rahhal, SM, Alonso, L, Palanca-Sanfrancisco, JM, Sanchis-Gimeno, JA. (2003). Corneal thickness values before and after oxybuprocaine 0.4% eye drops. Cornea. 22. 527-532
  • Kiely, PM, Carney, LG, Smith, G. (1983). Menstrual cycle variations of corneal topography and thickness. Am J Optom Physiol Opt. 60. 822-829
  • Sanchís-Gimeno, JA, Lleó-Pérez, A, Alonso, L, Rahhal, MS. (2005). Paquimetría orbscan: diferencias entre observadores al realizar mediciones del espesor corneal. Arch Soc Esp Oftalmol. 80. 283-287
  • Marsich, MW, Bullimore, MA. (2000). The repeatability of corneal thickness measures. Cornea. 19. 792-795
  • Giraldez Fernández, MJ, Díaz Rey, A, Cerviño, A, Yebra-Pimentel, E. (2002). A comparison of two pachymetric systems: silt-scanning and ultrasonic. CLAO J. 28. 221-223
  • Lattimore, MR Jr, Kaupp, S, Schallhorn, S, Lewis, R 4th. (1999). Orbscan pachymetry: implications of a repeated measures and diurnal variation analysis. Ophthalmology. 106. 977-981
  • Liu, Z, Huang, AJ, Pflugfelder, SC. (1999). Evaluation of corneal thickness and topography in normal eyes using the Orbscan corneal topography system. Br J Ophthalmol. 83. 774-778
  • Cho, P, Cheung, SW. (2002). Repeatability of corneal thickness measurements made by a scanning slit topography system. Ophthalmic Physiol Opt. 22. 505-510
  • Pallikaris, IG, Kymionis, GD, Astyrakakis, NI. (2001). Corneal ectasia induced by laser in situ keratomileusis. J Cataract Refract Surg. 27. 1796-1802
  • Rao, SN, Epstein, RJ. (2002). Early onset ectasia following laser in situ keratomileusus: case report and literature review. J Refract Surg. 18. 177-184
  • Miyata, K, Tokunaga, T, Nakahara, M, Ohtani, S, Nejima, R, Kiuchi, T. (2004). Residual bed thickness and corneal forward shift after laser in situ keratomileusis. J Cataract Refract Surg. 30. 1067-1072
  • Ghose, S, Garodia, VK, Sachdev, MS, Kumar, H, Biswas, NR, Pandey, RM. (2001). Evaluation of potentiating effect of a drop of lignocaine on tropicamide-induced mydriasis. Invest Ophthalmol Vis Sci. 42. 1581-1585
  • Cho, P, Brown, B. (1995). The effect of benoxinate on the tear stability of Hong Kong-Chinese. Ophthalmic Physiol Opt. 15. 299-304
  • Blades, KJ, Murphy, PJ, Patel, S. (1999). Tear thinning time and topical anesthesia as assessed using the HIRCAL grid and the NCCA. Optom Vis Sci. 76. 164-169
  • Pfister, RR, Burstein, N. (1976). The effects of ophthalmic drugs, vehicles, and preservatives on corneal epithelium: a scanning electron microscope study. Invest Ophthalmol. 15. 246-259
  • Silbert, JA. (1994). Anterior segment complications of contact lens wear. Churchill Livingstone. New York.
Data source: Dialnet