Protocolo diagnóstico del hiperandrogenismo adrenal

  1. E. Fernández-Rodríguez 1
  2. I. Bernabeu 2
  3. F.F. Casanueva 2
  1. 1 Complejo Hospitalario Universitario de Ourense. Orense. España
  2. 2 Complexo Hospitalario Universitario de Santiago
    info

    Complexo Hospitalario Universitario de Santiago

    Santiago de Compostela, España

    ROR https://ror.org/00mpdg388

Journal:
Medicine: Programa de Formación Médica Continuada Acreditado

ISSN: 0304-5412

Year of publication: 2016

Issue Title: Enfermedades endocrinológicas y metabólicas (II) Patología suprarrenal

Series: 12

Issue: 14

Pages: 816-819

Type: Article

DOI: 10.1016/J.MED.2016.06.016 DIALNET GOOGLE SCHOLAR

More publications in: Medicine: Programa de Formación Médica Continuada Acreditado

Abstract

Introduction Hyperandrogenism is defined as the clinical syndrome resulting from excess circulating androgens, either due to an excess production or to an increase in androgen receptor sensitivity. Aetiology The condition can have an ovarian, adrenal gland or exogenous origin. The most common cause of the condition is polycystic ovary syndrome, characterised by menstrual disorders, clinical and/or biochemical hyperandrogenism and polycystic ovarian morphology. Among the adrenal causes, congenital adrenal hyperplasia (through autosomal recessive inheritance) is characterised by enzyme deficits in the cortisol synthesis chain resulting in an increase in precursors to enzyme deficiency. Clinical features Patients clinically progress with adrenal insufficiency and signs of virilisation. Diagnosis Diagnosis is based in the detection of high levels of androgens and in the establishment of its origin. Treatment The treatment varies according to the cause of the hyperandrogenism.

Bibliographic References

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Data source: Dialnet