Enfermedades de las glándulas adrenales. Insuficiencia suprarrenal primaria

  1. E. Fernández-Rodríguez 1
  2. I. Bernabeu 2
  3. C. Guillín 2
  4. F.F. Casanueva 2
  1. 1 Complejo Hospitalario Universitario de Ourense. Orense. España
  2. 2 Complexo Hospitalario Universitario de Santiago
    info

    Complexo Hospitalario Universitario de Santiago

    Santiago de Compostela, España

    ROR https://ror.org/00mpdg388

Journal:
Medicine: Programa de Formación Médica Continuada Acreditado

ISSN: 0304-5412

Year of publication: 2016

Issue Title: Enfermedades endocrinológicas y metabólicas (II) Patología suprarrenal

Series: 12

Issue: 14

Pages: 775-780

Type: Article

DOI: 10.1016/J.MED.2016.06.010 DIALNET GOOGLE SCHOLAR

More publications in: Medicine: Programa de Formación Médica Continuada Acreditado

Abstract

Background Primary adrenal insufficiency or Addison's disease is characterised by the deficient production of hormones in the adrenal cortex, i.e., mineralocorticoids, glucocorticoids and androgens. Aetiology The most common aetiology in our community is autoimmune adrenalitis, and it is frequently associated with other immunologically based diseases. Symptoms In chronic cases, the clinical presentation of Addison's disease varies considerably and is insidious and progressive, constituting a medical emergency in cases of acute presentation and requiring immediate supportive treatment. Diagnosis The diagnosis is based mainly on the demonstration of low cortisol levels, high adrenocorticotropic hormone levels and a lack of cortisol response under stimulation with adrenocorticotropic hormone. Treatment The treatment consists of replacing the deficient hormones, especially glucocorticoids and mineralocorticoids, adjusting the dose according to the clinical response.

Bibliographic References

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Data source: Dialnet