Feocromocitoma y paraganglioma

  1. C. Guillín 1
  2. I. Bernabeu 1
  3. I.A. Rodríguez-Gómez 2
  4. F.F. Casanueva 2
  1. 1 Complexo Hospitalario Universitario de Santiago
    info

    Complexo Hospitalario Universitario de Santiago

    Santiago de Compostela, España

    ROR https://ror.org/00mpdg388

  2. 2 Unidad de Endocrinología y Nutrición. Hospital HM Modelo. La Coruña. España
Journal:
Medicine: Programa de Formación Médica Continuada Acreditado

ISSN: 0304-5412

Year of publication: 2016

Issue Title: Enfermedades endocrinológicas y metabólicas (II) Patología suprarrenal

Series: 12

Issue: 14

Pages: 795-801

Type: Article

DOI: 10.1016/J.MED.2016.06.013 DIALNET GOOGLE SCHOLAR

More publications in: Medicine: Programa de Formación Médica Continuada Acreditado

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Abstract

Introduction Chromaffin tumors of the adrenal medulla and the sympathetic ganglia are known as pheochromocytoma and paraganglioma, respectively. They are rare diseases, in most cases histologically benign, but potentially lethal due to the overproduction of catecholamines. History and clinical examination Clinical presentation depends on the activation of adrenergic receptors. Usually patients have labile and refractory hypertension, and other signs and symptoms, which include the classic triad (headache, sweating and tachycardia), adrenal paroxysms, hypertensive retinopathy, cardiomyopathy or anorexia, among others. Evaluation After establishing the biochemical confirmation of catecholamine excess, imaging techniques of choice to locate the tumor are the computed tomography and the magnetic resonance. Treatment Treatment of choice is the complete resection of the tumor, only after a correct alpha and beta adrenergic blockade, in order to control blood pressure and prevent intraoperative paroxysms.

Bibliographic References

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  • Lenders JW, Duh QY, Eisenhofer G, Giménez-Roqueplo AP, GrebeSK, Murad MH, et al. Pheochromocytoma and paraganglioma: anendocri-nesocietyclinicalpracticeguideline. J ClinEndocrinolMetab. 2014;99(6): 1915-42.
  • Martins R, Bugalho MJ. Paragangliomas/pheochromocytomas: clinicallyorientedgenetictesting. Int J Endocrinol. 2014;2014:794187.
Data source: Dialnet