Cardiopericardial and systemic inflammatory response in patients undergoing cardiac surgery

Abstract

The inflammatory response to cardiac surgery is partially responsible of many postoperative complications like the systemic inflammatory response syndrome and the respiratory distress syndrome. The pathophysiology of the inflammatory response was widely studied and many inflammatory mediators have been detected. However, most of the studies focused on the systemic component of the inflammatory response without adequately considering the local cardiopericardiac reaction. The pericardium and edpicardiac adipose tissue can actively synthesize and secrete various mediators. It is highly possible that there is a correlation but the local and systemic types of inflammatory response. The aim of this study isto study and quantify the local cardiopericardiac component of the inflammatory response that follows cardiac surgery.