Publicacións (26) Publicacións nas que participase algún/ha investigador/a Ver datos de investigación referenciados.

filter_list Pharmacology

2024

  1. Chemical sensors for the early diagnosis of bacterial resistance to β-lactam antibiotics

    Bioorganic Chemistry, Vol. 150

  2. Disseny de metal·lopèptids: la combinació de computació i experiments per arribar a la racionalització

    Revista de la Societat Catalana de Química, Núm. 23, pp. 35-43

  3. High-affinity A/T-rich DNA binding with a dimeric bisbenzamidine

    NAR Molecular Medicine, Vol. 1, Núm. 4

  4. Impact of transferable β-lactamases and intrinsic AmpC amino acid substitutions on the activity of cefiderocol against wild-type and iron uptake-deficient mutants of Pseudomonas aeruginosa

    The Journal of antimicrobial chemotherapy, Vol. 79, Núm. 11, pp. 3023-3028

  5. In vivo emergence of resistance to ceftazidime/avibactam through modification of chromosomal AmpC β-lactamase in Klebsiella aerogenes

    Antimicrobial Agents and Chemotherapy, Vol. 68, Núm. 12

  6. Novel Penicillin-Based Sulfone-Siderophore Conjugates for Restoring β-Lactam Antibiotic Efficacy

    ACS Omega, Vol. 9, Núm. 24, pp. 26484-26494

2023

  1. Antimicrobial Activity of Cefiderocol against the Carbapenemase-Producing Enterobacter cloacae Complex and Characterization of Reduced Susceptibility Associated with Metallo-β-Lactamase VIM-1

    Antimicrobial agents and chemotherapy, Vol. 67, Núm. 5, pp. e0150522

  2. Interplay between OXA-10 β-Lactamase Production and Low Outer-Membrane Permeability in Carbapenem Resistance in Enterobacterales

    Antibiotics, Vol. 12, Núm. 6

2021

  1. 6-Halopyridylmethylidene Penicillin-Based Sulfones Efficiently Inactivate the Natural Resistance of Pseudomonas aeruginosa to β-Lactam Antibiotics

    Journal of Medicinal Chemistry, Vol. 64, Núm. 9, pp. 6310-6328

  2. Activity of imipenem, meropenem, cefepime, and sulbactam in combination with the β-lactamase inhibitor ln-1-255 against acinetobacter spp.

    Antibiotics, Vol. 10, Núm. 2, pp. 1-15

  3. Bicyclic Boronate β-Lactamase Inhibitors: The Present Hope against Deadly Bacterial Pathogens

    Advanced Therapeutics, Vol. 4, Núm. 5

  4. Crambescin C1 Acts as A Possible Substrate of iNOS and eNOS Increasing Nitric Oxide Production and Inducing In Vivo Hypotensive Effect

    Frontiers in Pharmacology, Vol. 12

  5. Molecular Basis of Bicyclic Boronate β-Lactamase Inhibitors of Ultrabroad Efficacy – Insights From Molecular Dynamics Simulation Studies

    Frontiers in Microbiology, Vol. 12

2020

  1. 6-Arylmethylidene Penicillin-Based Sulfone Inhibitors for Repurposing Antibiotic Efficiency in Priority Pathogens

    Journal of Medicinal Chemistry, Vol. 63, Núm. 7, pp. 3737-3755

  2. Antibody-PROTAC Conjugates Enable HER2-Dependent Targeted Protein Degradation of BRD4

    ACS Chemical Biology, Vol. 15, Núm. 6, pp. 1306-1312

  3. Characterization of Locally Excited and Charge-Transfer States of the Anticancer Drug Lapatinib by Ultrafast Spectroscopy and Computational Studies

    Chemistry - A European Journal, Vol. 26, Núm. 68, pp. 15922-15930

  4. β-Lactamase Inhibitors to Restore the Efficacy of Antibiotics against Superbugs

    Journal of Medicinal Chemistry, Vol. 63, Núm. 5, pp. 1859-1881

2019

  1. Challenging antimicrobial susceptibility and evolution of resistance (oxa-681) during treatment of a long-term nosocomial infection caused by a pseudomonas aeruginosa ST175 Clone

    Antimicrobial Agents and Chemotherapy, Vol. 63, Núm. 10

  2. Hydroxylammonium derivatives for selective active-site lysine modification in the anti-virulence bacterial target DHQ1 enzyme

    Organic Chemistry Frontiers, Vol. 6, Núm. 17, pp. 3127-3135

  3. Synthesis of rigidified shikimic acid derivatives by ring-closing metathesis to imprint inhibitor efficacy against shikimate kinase enzyme

    Organic Chemistry Frontiers, Vol. 6, Núm. 14, pp. 2514-2528