Farma SNC-EO
Farmacoloxía do Sistema Nervioso Central e do Estrés Oxidativo
Publicacións (11) Publicacións nas que participase algún/ha investigador/a
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Pharmacology
2025
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Gamma-Decanolactone Increases Stress Resistance and Improves Toxicity Parameters on the Caenorhabditis elegans Alternative Model
Journal of Applied Toxicology, Vol. 45, Núm. 2, pp. 339-349
2023
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8-Amide and 8-carbamate substitution patterns as modulators of 7-hydroxy-4-methylcoumarin's antidepressant profile: Synthesis, biological evaluation and docking studies
European Journal of Medicinal Chemistry, Vol. 248
2021
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Gamma-decanolactone: Preliminary evaluation as potential antiparkinsonian drug
European Journal of Pharmacology, Vol. 906
2020
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Discovery and optimization of 3-thiophenylcoumarins as novel agents against Parkinson's disease: Synthesis, in vitro and in vivo studies
Bioorganic Chemistry, Vol. 101
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Novel coumarin-pyridazine hybrids as selective MAO-B inhibitors for the Parkinson's disease therapy
Bioorganic Chemistry, Vol. 104
2018
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Alkaloids as MAO-A inhibitors: Towards the final solution for depression and anxiety
Psychiatric and Mood Diseases and the Natural Compounds: An Approach to the Future Medical Tool (Nova Science Publishers, Inc.), pp. 169-192
2014
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Comparison of the antidepressive effects of trans-resveratrol and 5-methoxy-7H-dibenzo[de,h]quinolin-7-one.
Current topics in medicinal chemistry, Vol. 14, Núm. 2, pp. 234-238
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Synthesis, pharmacological study and docking calculations of new benzo[f]coumarin derivatives as dual inhibitors of enzymatic systems involved in neurodegenerative diseases
Future Medicinal Chemistry, Vol. 6, Núm. 4, pp. 371-383
2000
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Binding and preliminary evaluation of 5-hydroxy- and 10-hydroxy- 2,3,12,12a-tetrahydro-1H-[1]benzoxepino[2,3,4-ij]isoquinolines as dopamine receptor ligands
Journal of Medicinal Chemistry, Vol. 43, Núm. 4, pp. 599-608
1999
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Conformationally constrained butyrophenones with mixed dopaminergic (D2) and serotoninergic (5-HT2(A), 5-HT2(C)) affinities: Synthesis, pharmacology, 3D-QSAR, and molecular modeling of (aminoalkyl)benzo- and - thienocycloalkanones as putative atypical antipsychotics
Journal of Medicinal Chemistry, Vol. 42, Núm. 15, pp. 2774-2797
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In vivo effects of new inhibitors of catechol-O-methyl transferase
British Journal of Pharmacology, Vol. 126, Núm. 7, pp. 1667-1673