Publicacións (10) Publicacións nas que participase algún/ha investigador/a

filter_list Organic Chemistry

2023

  1. 8-Amide and 8-carbamate substitution patterns as modulators of 7-hydroxy-4-methylcoumarin's antidepressant profile: Synthesis, biological evaluation and docking studies

    European Journal of Medicinal Chemistry, Vol. 248

2020

  1. Discovery and optimization of 3-thiophenylcoumarins as novel agents against Parkinson's disease: Synthesis, in vitro and in vivo studies

    Bioorganic Chemistry, Vol. 101

  2. Novel coumarin-pyridazine hybrids as selective MAO-B inhibitors for the Parkinson's disease therapy

    Bioorganic Chemistry, Vol. 104

2017

  1. MAO inhibitory activity of bromo-2-phenylbenzofurans: Synthesis,: in vitro study, and docking calculations

    MedChemComm, Vol. 8, Núm. 9, pp. 1788-1796

2014

  1. Comparison of the antidepressive effects of trans-resveratrol and 5-methoxy-7H-dibenzo[de,h]quinolin-7-one.

    Current topics in medicinal chemistry, Vol. 14, Núm. 2, pp. 234-238

  2. Synthesis, pharmacological study and docking calculations of new benzo[f]coumarin derivatives as dual inhibitors of enzymatic systems involved in neurodegenerative diseases

    Future Medicinal Chemistry, Vol. 6, Núm. 4, pp. 371-383

2003

  1. Synthesis of glycosyl derivatives as dopamine prodrugs: Interaction with glucose carrier GLUT-1

    Organic and Biomolecular Chemistry, Vol. 1, Núm. 5, pp. 767-771

2000

  1. Binding and preliminary evaluation of 5-hydroxy- and 10-hydroxy- 2,3,12,12a-tetrahydro-1H-[1]benzoxepino[2,3,4-ij]isoquinolines as dopamine receptor ligands

    Journal of Medicinal Chemistry, Vol. 43, Núm. 4, pp. 599-608

  2. Conformationally constrained butyrophenones with affinity for dopamine (D1, D2, D4) and serotonin (5-HT(2A), 5-HT(2B), 5-HT(2C)) receptors: Synthesis of aminomethylbenzo[b]furanones and their evaluation as antipsychotics

    Journal of Medicinal Chemistry, Vol. 43, Núm. 24, pp. 4678-4693

1999

  1. Conformationally constrained butyrophenones with mixed dopaminergic (D2) and serotoninergic (5-HT2(A), 5-HT2(C)) affinities: Synthesis, pharmacology, 3D-QSAR, and molecular modeling of (aminoalkyl)benzo- and - thienocycloalkanones as putative atypical antipsychotics

    Journal of Medicinal Chemistry, Vol. 42, Núm. 15, pp. 2774-2797