Publicacións (126) Publicacións nas que participase algún/ha investigador/a

filter_list Organic Chemistry

2024

  1. Benzylhydroxamic acids as inhibitors of insulin regulated aminopeptidase (IRAP)

    European Journal of Medicinal Chemistry Reports, Vol. 12

  2. N-Adamantyl-1-alkyl-4-oxo-1,4-dihydroquinoline-3-carboxamide Derivatives as Fluorescent Probes to Detect Microglia Activation through the Imaging of Cannabinoid Receptor Subtype 2 (CB2R)

    Journal of Medicinal Chemistry, Vol. 67, Núm. 13, pp. 11003-11023

  3. Telescoped One-Pot Strategy for the Assembly of cis-4-Hydroxy-l-Prolyl Amides

    ACS Sustainable Chemistry and Engineering, Vol. 12, Núm. 46, pp. 16986-16998

2023

  1. Development of Fluorescent 4-[4-(3H-Spiro[isobenzofuran-1,4′-piperidin]-1′-yl)butyl]indolyl Derivatives as High-Affinity Probes to Enable the Study of σ Receptors via Fluorescence-Based Techniques

    Journal of Medicinal Chemistry, Vol. 66, Núm. 6, pp. 3798-3817

  2. Multicomponent Reaction-Assisted Drug Discovery: A Time- and Cost-Effective Green Approach Speeding Up Identification and Optimization of Anticancer Drugs

    International Journal of Molecular Sciences, Vol. 24, Núm. 7

  3. N-adamantyl-anthranil amide derivatives: New selective ligands for the cannabinoid receptor subtype 2 (CB2R)

    European Journal of Medicinal Chemistry, Vol. 248

  4. Stapling Amantadine to Melanostatin Neuropeptide: Discovery of Potent Positive Allosteric Modulators of the D2 Receptors

    ACS Medicinal Chemistry Letters, Vol. 14, Núm. 12, pp. 1656-1663

2022

  1. Enantiomeric Separation and Molecular Modelling of Bioactive 4-Aryl-3,4-dihydropyrimidin-2(1H)-one Ester Derivatives on Teicoplanin-Based Chiral Stationary Phase

    Separations, Vol. 9, Núm. 1

  2. Exploring Non-orthosteric Interactions with a Series of Potent and Selective A3Antagonists

    ACS Medicinal Chemistry Letters, Vol. 13, Núm. 2, pp. 243-249

  3. Isolation and structural characterization of stable carbamic-carbonic anhydrides: an experimental and computational study

    Organic Chemistry Frontiers, Vol. 9, Núm. 8, pp. 2154-2163

  4. Optimization of 2-Amino-4,6-diarylpyrimidine-5-carbonitriles as Potent and Selective A1Antagonists

    Journal of Medicinal Chemistry, Vol. 65, Núm. 3, pp. 2091-2106

2021

  1. Discovery of New Potent Positive Allosteric Modulators of Dopamine D2Receptors: Insights into the Bioisosteric Replacement of Proline to 3-Furoic Acid in the Melanostatin Neuropeptide

    Journal of Medicinal Chemistry, Vol. 64, Núm. 9, pp. 6209-6220

  2. Identification of V6.51L as a selectivity hotspot in stereoselective A2B adenosine receptor antagonist recognition

    Scientific Reports, Vol. 11, Núm. 1

  3. Potent and Subtype-Selective Dopamine D2Receptor Biased Partial Agonists Discovered via an Ugi-Based Approach

    Journal of Medicinal Chemistry, Vol. 64, Núm. 12, pp. 8710-8726

  4. Stereoselective Synthesis of Hydrindane and Hydroazulene Derivatives by Transannular Cyclization of Nine- And Ten-Membered Carbocycles

    Journal of Organic Chemistry, Vol. 86, Núm. 19, pp. 13684-13692

2020

  1. A sustainable strategy for the assembly of Glypromate® and its structurally-related analogues by tandem sequential peptide coupling

    Green Chemistry, Vol. 22, Núm. 11, pp. 3584-3596

  2. Nitrogen-Walk Approach to Explore Bioisosteric Replacements in a Series of Potent A2B Adenosine Receptor Antagonists

    Journal of medicinal chemistry, Vol. 63, Núm. 14, pp. 7721-7739

2019

  1. Mechanistic insights for the transprotection of tertiary amines with Boc2O: Via charged carbamates: Access to both enantiomers of 2-azanorbornane-3- exo -carboxylic acids

    Organic Chemistry Frontiers, Vol. 6, Núm. 20, pp. 3540-3554

  2. Multicatalysis Combining 3D-Printed Devices and Magnetic Nanoparticles in One-Pot Reactions: Steps Forward in Compartmentation and Recyclability of Catalysts

    ACS Applied Materials and Interfaces, Vol. 11, Núm. 28, pp. 25283-25294

  3. Trifluorinated Pyrimidine-Based A2B Antagonists: Optimization and Evidence of Stereospecific Recognition

    Journal of Medicinal Chemistry, Vol. 62, Núm. 20, pp. 9315-9330