Publicacións (15) Publicacións nas que participase algún/ha investigador/a

filter_list Molecular Medicine

2024

  1. N-Adamantyl-1-alkyl-4-oxo-1,4-dihydroquinoline-3-carboxamide Derivatives as Fluorescent Probes to Detect Microglia Activation through the Imaging of Cannabinoid Receptor Subtype 2 (CB2R)

    Journal of Medicinal Chemistry, Vol. 67, Núm. 13, pp. 11003-11023

2023

  1. Multicomponent Reaction-Assisted Drug Discovery: A Time- and Cost-Effective Green Approach Speeding Up Identification and Optimization of Anticancer Drugs

    International Journal of Molecular Sciences, Vol. 24, Núm. 7

  2. Stapling Amantadine to Melanostatin Neuropeptide: Discovery of Potent Positive Allosteric Modulators of the D2 Receptors

    ACS Medicinal Chemistry Letters, Vol. 14, Núm. 12, pp. 1656-1663

2021

  1. 3,4-Dihydropyrimidin-2(1H)-ones as Antagonists of the Human A2B Adenosine Receptor: Optimization, Structure-Activity Relationship Studies, and Enantiospecific Recognition

    Journal of medicinal chemistry, Vol. 64, Núm. 1, pp. 458-480

  2. Discovery of New Potent Positive Allosteric Modulators of Dopamine D2Receptors: Insights into the Bioisosteric Replacement of Proline to 3-Furoic Acid in the Melanostatin Neuropeptide

    Journal of Medicinal Chemistry, Vol. 64, Núm. 9, pp. 6209-6220

2017

  1. 3-Oxopyridazin-5-yl-Chalcone Hybrids: Potent Antiplatelet Agents That Prevent Glycoprotein IIb/IIIa Activation

    ChemistrySelect, Vol. 2, Núm. 17, pp. 4920-4933

  2. Computer-aided design of multi-target ligands at A1R, A2AR and PDE10A, key proteins in neurodegenerative diseases

    Journal of Cheminformatics, Vol. 9, Núm. 1

  3. Structure-Based Design of Potent and Selective Ligands at the Four Adenosine Receptors

    Molecules, Vol. 22, Núm. 11

  4. Structure-based rational design of adenosine receptor ligands

    Current Topics in Medicinal Chemistry, Vol. 17, Núm. 1, pp. 40-58

  5. Synthesis and characterization of a new bivalent ligand combining caffeine and docosahexaenoic acid

    Molecules, Vol. 22, Núm. 3

2013

  1. Patents of bio-active compounds based on computer-aided drug discovery techniques

    Frontiers in Bioscience - Elite, Vol. 5 E, Núm. 2, pp. 399-407

2010

  1. Design, synthesis, and evaluation of antineoplastic activity of novel carbocyclic nucleosides

    Molecular Informatics, Vol. 29, Núm. 3, pp. 213-231

2009

  1. Theoretical prediction of antiproliferative activity against murine leukemia tumor cell line (L1210). 3D-morse descriptor and its application in computational chemistry)

    QSAR and Combinatorial Science, Vol. 28, Núm. 1, pp. 98-110

2007

  1. Probing the anticancer activity of nucleoside analogues: A QSAR model approach using an internally consistent training set

    Journal of Medicinal Chemistry, Vol. 50, Núm. 7, pp. 1537-1545

2003

  1. Carbocyclic analogues of nucleosides from bis-(hydroxymethyl)-cyclopentane: Synthesis, antiviral and cytostatic activities of adenosine, inosine and uridine analogues

    Chemical and Pharmaceutical Bulletin, Vol. 51, Núm. 9, pp. 1060-1063